Natural Zeitgebers Under Temperate Conditions Cannot Compensate for the Loss of a Functional Circadian Clock in Timing of a Vital Behavior in Drosophila

Natural Zeitgebers Under Temperate Conditions Cannot Compensate for the Loss of a Functional Circadian Clock in Timing of a Vital Behavior in Drosophila

Natural Zeitgebers Under Temperate Conditions Cannot Compensate for the Loss of a Functional Circadian Clock in Timing of a Vital Behavior in Drosophila

The adaptive significance of adjusting behavioral actions to the best time of the day appears apparent. Laboratory research implicated an essential position of circadian clocks in behavioral timing and rhythmicity. But, latest research on clock-mutant animals questioned this significance below extra naturalistic settings, as numerous clock mutants confirmed almost regular diel exercise rhythms below seminatural zeitgeber circumstances.
We right here report proof that correct timing of eclosion, a significant habits of the fruit fly Drosophila melanogaster, requires a purposeful molecular clock below quasi-natural circumstances. In distinction to wild-type flies, interval01 mutants with a faulty molecular clock confirmed impaired rhythmicity and gating in a temperate setting even within the presence of a full complement of abiotic zeitgebers. Though interval01 mutants nonetheless eclosed throughout a sure time window in the course of the day, this time window was a lot broader and loosely outlined, and rhythmicity was decrease or misplaced as categorized by numerous statistical measures. Furthermore, peak eclosion time turned extra inclined to variable day-to-day modifications of sunshine.
In distinction, flies with impaired peptidergic interclock signaling (Pdf01 and han5304 PDF receptor mutants) eclosed largely rhythmically with regular gate sizes, much like wild-type controls. Our outcomes recommend that the presence of pure zeitgebers isn’t adequate, and a purposeful molecular clock is required to induce steady temporal eclosion patterns in flies below temperate circumstances with appreciable day-to-day variation in gentle depth and temperature. Temperate zeitgebers are, nonetheless, adequate to functionally rescue a lack of PDF-mediated clock-internal and -output signaling.

Nanda-Hamner Curves Present Large Latitudinal Variation however No Circadian Elements in Drosophila Montana Photoperiodism

Insect species with a large distribution provide an important alternative to hint latitudinal variation within the photoperiodic regulation of traits essential in copy and stress tolerances. We measured this variation within the photoperiodic time-measuring system underlying reproductive diapause in Drosophila montana, utilizing a Nanda-Hamner (NH) protocol. Not one of the research strains confirmed diel rhythmicity in feminine diapause proportions below a continuing day size (12 h) and ranging night time lengths in photoperiods starting from 16 to 84 h at 16°C. Within the northernmost strains (above 55°N), almost all females entered diapause below all photoperiods and about half of them even in steady darkness, whereas the females of the southern strains confirmed excessive diapause proportions solely within the circadian 24 h photoperiod.
Important correlation between the strains’ imply diapause proportions in ≥ 24 h photoperiods and important day size (CDL; half of the females enter diapause) suggests at the least partial causal connection between the traits. Apparently, females of the northern strains entered diapause even in ≤ 24 h photoperiods, the place the night time size was shorter than their important night time size (24 h – CDL), however the place the females skilled a better variety of Gentle:Darkish cycles than in 24 h photoperiods.
NH experiments, carried out on the management and choice strains in our earlier choice experiment, and accomplished right here, gave comparable outcomes and confirmed that choice for shorter, southern-type CDL decreases feminine diapausing fee in non-circadian photoperiods. Total, our research exhibits that D. montana females measure night time size quantitatively, that the photoperiodic counter could play a distinguished however barely totally different position in further quick and further lengthy photoperiods and that northern strains present excessive stability towards perturbations within the photoperiod size and within the presence of LD cycles. These options are finest defined by the quantitative variations of the damped exterior coincidence mannequin.
Natural Zeitgebers Under Temperate Conditions Cannot Compensate for the Loss of a Functional Circadian Clock in Timing of a Vital Behavior in Drosophila

Interaction between intercourse willpower cascade and main signaling pathways throughout Drosophila eye improvement: Views for future analysis

Understanding molecular mechanisms of sexually dimorphic organ progress is a elementary downside of developmental biology. Current quantitative research confirmed that the Drosophila compound eye is a handy mannequin to review the willpower of the ultimate organ measurement. In Drosophila, females have bigger eyes than males and that is evident even after correction for the bigger physique measurement. Furthermore, feminine eyes embody extra ommatidia (photosensitive items) than male eyes and this distinction is specified on the third larval instar within the eye primordia referred to as eye imaginal discs. This will likely end in totally different visible capabilities between the 2 sexes and have behavioral penalties.
Regardless of rising proof on the genetic bases of eye measurement variation between totally different Drosophila species and strains, mechanisms accountable for within-species sexual dimorphism nonetheless stay elusive. Right here, we focus on a presumptive crosstalk between the intercourse willpower cascade and main signaling pathways throughout dimorphic eye improvement. Male- and female-specific isoforms of Doublesex (Dsx) protein are identified to regulate sex-specific differentiation within the somatic tissues. Nonetheless, no information on Dsx perform throughout eye disc progress and patterning are presently accessible.
Remarkably, Intercourse deadly (Sxl), the intercourse willpower change protein, was proven to straight have an effect on Hedgehog (Hh) and Notch (N) signaling within the Drosophila wing disc. The similarity of signaling pathways concerned within the wing and eye disc progress means that Sxl is perhaps built-in into regulation of eye improvement. Dsx position within the eye disc requires additional investigation. We focus on presently accessible information on sex-biased gene expression within the Drosophila eye and spotlight views for future research.

DNA polymerase theta suppresses mitotic crossing over

Polymerase theta-mediated finish becoming a member of (TMEJ) is a chromosome break restore pathway that is ready to rescue the lethality related to the lack of proteins concerned in early steps in homologous recombination (e.g., BRCA1/2). That is because of the capacity of polymerase theta (Pol θ) to make use of resected, 3′ single stranded DNA tails to restore chromosome breaks. These resected DNA tails are additionally the beginning substrate for homologous recombination. Nonetheless, it stays unknown if TMEJ can compensate for the lack of proteins concerned in additional downstream steps throughout homologous recombination. Right here we present that the Holliday junction resolvases SLX4 and GEN1 are required for viability within the absence of Pol θ in Drosophila melanogaster, and lack of all three proteins ends in excessive ranges of apoptosis.
Flies poor in Pol θ and SLX4 are extraordinarily delicate to DNA damaging brokers, and mammalian cells require both Pol θ or SLX4 to outlive. Our outcomes recommend that TMEJ and Holliday junction formation/decision share a standard DNA substrate, seemingly a homologous recombination intermediate, that when left unrepaired results in cell demise. One main consequence of Holliday junction decision by SLX4 and GEN1 is cancer-causing lack of heterozygosity as a consequence of mitotic crossing over. We measured mitotic crossovers in flies after a Cas9-induced chromosome break, and noticed that this mutagenic type of restore is elevated within the absence of Pol θ.

Monoclonal SSX4 Antibody (monoclonal) (M02), Clone: 3E11

APR10252G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human SSX4 (monoclonal) (M02). The antibodies are raised in mouse and are from clone 3E11. This antibody is applicable in WB and IF, E

Monoclonal ATP7B Antibody (monoclonal) (M01), Clone: 3E11

APG02168G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human ATP7B (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3E11. This antibody is applicable in WB, E

Monoclonal HIP1R Antibody (monoclonal) (M01), Clone: 3E11

APR12375G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human HIP1R (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3E11. This antibody is applicable in WB, E

Monoclonal TCF4 Antibody (monoclonal) (M01), Clone: 3E11

APR14413G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human TCF4 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3E11. This antibody is applicable in WB and IF

Monoclonal COPB Antibody (monoclonal) (M08), Clone: 3E11

APR15551G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human COPB (monoclonal) (M08). The antibodies are raised in mouse and are from clone 3E11. This antibody is applicable in E

Monoclonal FBL Antibody (monoclonal) (M09), Clone: 3E11

APR15927G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human FBL (monoclonal) (M09). The antibodies are raised in mouse and are from clone 3E11. This antibody is applicable in E

Monoclonal PDLIM5 Antibody (monoclonal) (M01), Clone: 3E11-F6

APR12791G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human PDLIM5 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3E11-F6. This antibody is applicable in WB and IF, E

Anti Mummichog Vitellogenin Monoclonal Antibody (Clone No. 3E11)

KH005
EUR 544
Description: The Anti Mummichog Vitellogenin Monoclonal Antibody (Clone No. 3E11) is available in Europe and for worldwide shipping via Gentaur.

Anti-Twist (3E11)

YF-MA10977 100 ug
EUR 363
Description: Mouse monoclonal to Twist

Anti-cvHSP (3E11)

YF-MA11450 100 ug
EUR 363
Description: Mouse monoclonal to cvHSP

Anti-AKT1 (3E11)

YF-MA11876 100 ug
EUR 363
Description: Mouse monoclonal to AKT1

Anti-OSGIN2 (3E11)

YF-MA12209 100 ug
EUR 363
Description: Mouse monoclonal to OSGIN2

Anti-FMRP (3E11)

YF-MA13101 100 ug
EUR 363
Description: Mouse monoclonal to FMRP

Anti-MCM3 (3E11)

YF-MA14152 100 ug
EUR 363
Description: Mouse monoclonal to MCM3

Anti-NHLH2 (3E11)

YF-MA14458 100 ug
EUR 363
Description: Mouse monoclonal to NHLH2

Anti-POMC (3E11)

YF-MA14807 100 ug
EUR 363
Description: Mouse monoclonal to POMC

Anti-RPL23A (3E11)

YF-MA15244 100 ug
EUR 363
Description: Mouse monoclonal to RPL23A

Anti-Psoriasin (3E11)

YF-MA15314 50 ug
EUR 363
Description: Mouse monoclonal to Psoriasin

Anti-Psoriasin (3E11)

YF-MA15315 200 ul
EUR 363
Description: Mouse monoclonal to Psoriasin

Anti-Osteopontin (3E11)

YF-MA15581 100 ug
EUR 363
Description: Mouse monoclonal to Osteopontin

Anti-TCF2 (3E11)

YF-MA15765 100 ug
EUR 363
Description: Mouse monoclonal to TCF2

Anti-KLF10 (3E11)

YF-MA15849 100 ug
EUR 363
Description: Mouse monoclonal to KLF10

Anti-ZNF187 (3E11)

YF-MA16192 100 ug
EUR 363
Description: Mouse monoclonal to ZNF187

Anti-CER1 (3E11)

YF-MA16795 100 ug
EUR 363
Description: Mouse monoclonal to CER1

Anti-TIP30 (3E11)

YF-MA17378 100 ug
EUR 363
Description: Mouse monoclonal to TIP30

Anti-CCRK (3E11)

YF-MA17926 100 ug
EUR 363
Description: Mouse monoclonal to CCRK

Anti-BTBD1 (3E11)

YF-MA18595 100 ug
EUR 363
Description: Mouse monoclonal to BTBD1

Anti-ALS2CR2 (3E11)

YF-MA18781 100 ug
EUR 363
Description: Mouse monoclonal to ALS2CR2

Anti-SPG (3E11)

YF-MA18829 50 ug
EUR 363
Description: Mouse monoclonal to SPG

Anti-MRPS36 (3E11)

YF-MA19657 100 ug
EUR 363
Description: Mouse monoclonal to MRPS36

Anti-MPO (3E11)

YF-MA20367 100 ug
EUR 363
Description: Mouse monoclonal to MPO

Anti-ARFGEF1 (3E11)

YF-MA20498 100 ug
EUR 363
Description: Mouse monoclonal to ARFGEF1

anti-HDAC3 (3E11)

LF-MA10133 100 ug
EUR 363
Description: Mouse monoclonal to HDAC3

Anti-ORC2 (3E11-1G5)

YF-MA10652 100 ug
EUR 363
Description: Mouse monoclonal to ORC2

Anti-PDLIM5 (3E11-F6)

YF-MA11302 100 ug
EUR 363
Description: Mouse monoclonal to PDLIM5

Anti-IkB beta (3E11)

YF-MA14442 100 ug
EUR 363
Description: Mouse monoclonal to IkB beta

anti-Progesteron Receptor (3E11)

LF-MA10230 100 ug
EUR 363
Description: Mouse monoclonal to Progesteron Receptor

Monoclonal Ku (p70/p80)Mouse Monoclonal Antibody [Clone KU729], Clone: KU729

AMM00210G 0.5ml
EUR 484
Description: A Monoclonal antibody against Human Ku (p70/p80)Mouse Monoclonal [Clone KU729]. The antibodies are raised in Mouse and are from clone KU729. This antibody is applicable in IF, FC

Monoclonal Mouse Bmi1 Antibody, Clone: 353CT22.4.4

AMM02383G 0.1ml
EUR 484
Description: A Monoclonal antibody against Human Mouse Bmi1. The antibodies are raised in Mouse and are from clone 353CT22.4.4. This antibody is applicable in WB, E

Monoclonal mouse Lplunc1 Antibody, Clone: 4H2

APR08492G 0.1ml
EUR 528
Description: A Monoclonal antibody against Human mouse Lplunc1. The antibodies are raised in Mouse and are from clone 4H2. This antibody is applicable in WB and IHC, FC, ICC, E

Monoclonal mouse Lplunc1 Antibody, Clone: 1F11E3

APR08493G 0.1ml
EUR 528
Description: A Monoclonal antibody against Human mouse Lplunc1. The antibodies are raised in Mouse and are from clone 1F11E3. This antibody is applicable in WB, E

Monoclonal mouse Splunc2 Antibody, Clone: 1F12

APR07136G 0.1ml
EUR 528
Description: A Monoclonal antibody against Human mouse Splunc2. The antibodies are raised in Mouse and are from clone 1F12. This antibody is applicable in WB and IHC, FC, ICC, E

Monoclonal CD28 FITC Monoclonal Antibody (Clone CD28.2), Clone: CD28.2

AMM00025G 0.05mg
EUR 396
Description: A Monoclonal antibody against Human CD28 FITC Monoclonal (Clone CD28.2). The antibodies are raised in Mouse and are from clone CD28.2. This antibody is applicable in FC

Monoclonal CD11c FITC Monoclonal Antibody (Clone 3.9), Clone: 3.9

APR15331G 50 tests
EUR 484
Description: A Monoclonal antibody against Human CD11c FITC Monoclonal (Clone 3.9). The antibodies are raised in Mouse and are from clone 3.9. This antibody is applicable in FC

Monoclonal NGFR Antibody (Clone # 8G3G10), Clone: Clone # 8G3G10

AMM06686G 0.1ml
EUR 484
Description: A Monoclonal antibody against Human NGFR (Clone # 8G3G10). The antibodies are raised in Mouse and are from clone Clone # 8G3G10. This antibody is applicable in WB and IF, FC

Monoclonal S100A8 Antibody (Clone IMG48M7C7), Clone: Clone IMG48M7C7

AMM00015G 0.1mg
EUR 528
Description: A Monoclonal antibody against Human S100A8 (Clone IMG48M7C7). The antibodies are raised in Mouse and are from clone Clone IMG48M7C7. This antibody is applicable in WB and IHC

Monoclonal PDGFR Antibody (Clone # 275CT1), Clone: Clone # 275CT1

AMM00020G 0.05ml
EUR 484
Description: A Monoclonal antibody against Human PDGFR (Clone # 275CT1). The antibodies are raised in Mouse and are from clone Clone # 275CT1. This antibody is applicable in WB

Monoclonal CST3 Antibody (monoclonal), Clone: 1H4

AMM03425G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human CST3 (monoclonal). The antibodies are raised in Mouse and are from clone 1H4. This antibody is applicable in WB

Monoclonal TNFSF18 Antibody (monoclonal), Clone: 2E11

AMM04221G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human TNFSF18 (monoclonal). The antibodies are raised in mouse and are from clone 2E11. This antibody is applicable in WB, E

Monoclonal FTL Antibody (monoclonal), Clone: 4G7

AMM04622G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human FTL (monoclonal). The antibodies are raised in Mouse and are from clone 4G7. This antibody is applicable in WB, E

Mouse Anti-Mouse TIGIT Monoclonal antibody, clone 1G9

CABT-L4298-1mg 1 mg
EUR 897

Mouse Anti-Mouse TIGIT Monoclonal antibody, clone 1G9

CABT-L4298-5mg 5 mg
EUR 2405

Mouse Anti-Mouse CD22 Monoclonal antibody, clone Cy34.1

CABT-L4309-1mg 1 mg
EUR 897

Mouse Anti-Mouse CD22 Monoclonal antibody, clone Cy34.1

CABT-L4309-5mg 5 mg
EUR 2405

Mouse Anti-Mouse NK1.1 Monoclonal antibody, clone PK136

CABT-L4348-1mg 1 mg
EUR 897

Mouse Anti-Mouse NK1.1 Monoclonal antibody, clone PK136

CABT-L4348-5mg 5 mg
EUR 2405

Mouse Anti-Mouse CD45.2 Monoclonal antibody, clone 104.2

CABT-L4528-1mg 1 mg
EUR 897

Mouse Anti-Mouse CD45.2 Monoclonal antibody, clone 104.2

CABT-L4528-5mg 5 mg
EUR 2405

Mouse Anti-Albendazole monoclonal antibody, clone ABZ2

CABT-L3042-100ug 100 ug
EUR 533

Mouse Anti-Albendazole monoclonal antibody, clone ABZ2

CABT-L3042-1mg 1 mg
EUR 1313

Mouse Anti-Fluoroquinolones monoclonal antibody, clone FK2

CABT-L3046-100ug 100 ug
EUR 533

Mouse Anti-Fluoroquinolones monoclonal antibody, clone FK2

CABT-L3046-1mg 1 mg
EUR 1313

Mouse Anti-Fluoroquinolones monoclonal antibody, clone FK3

CABT-L3047-100ug 100 ug
EUR 533

Mouse Anti-Fluoroquinolones monoclonal antibody, clone FK3

CABT-L3047-1mg 1 mg
EUR 1313

Mouse Anti-Cyproheptadine monoclonal antibody, clone CHD

CABT-L3052-100ug 100 ug
EUR 533

Mouse Anti-Cyproheptadine monoclonal antibody, clone CHD

CABT-L3052-1mg 1 mg
EUR 1313

Mouse Anti-Clonidine monoclonal antibody, clone CLD

CABT-L3053-100ug 100 ug
EUR 533

Mouse Anti-Clonidine monoclonal antibody, clone CLD

CABT-L3053-1mg 1 mg
EUR 1313

Mouse Anti-Diaveridine monoclonal antibody, clone DVD

CABT-L3055-100ug 100 ug
EUR 533

Mouse Anti-Diaveridine monoclonal antibody, clone DVD

CABT-L3055-1mg 1 mg
EUR 1313

Mouse Anti-Ormetoprim monoclonal antibody, clone OMP

CABT-L3056-100ug 100 ug
EUR 533

Mouse Anti-Ormetoprim monoclonal antibody, clone OMP

CABT-L3056-1mg 1 mg
EUR 1313

Mouse Anti-Clindamycin monoclonal antibody, clone CDM

CABT-L3057-100ug 100 ug
EUR 533

Mouse Anti-Clindamycin monoclonal antibody, clone CDM

CABT-L3057-1mg 1 mg
EUR 1313

Mouse Anti-Azithromycin monoclonal antibody, clone ATM

CABT-L3058-100ug 100 ug
EUR 533

Mouse Anti-Azithromycin monoclonal antibody, clone ATM

CABT-L3058-1mg 1 mg
EUR 1313

Mouse Anti-Roxithromycin monoclonal antibody, clone RTM

CABT-L3059-100ug 100 ug
EUR 533

Mouse Anti-Roxithromycin monoclonal antibody, clone RTM

CABT-L3059-1mg 1 mg
EUR 1313

Mouse Anti-Clarithromycin monoclonal antibody, clone CTM

CABT-L3060-100ug 100 ug
EUR 533

Mouse Anti-Clarithromycin monoclonal antibody, clone CTM

CABT-L3060-1mg 1 mg
EUR 1313

Mouse Anti-Spiramycin monoclonal antibody, clone SPM

CABT-L3062-100ug 100 ug
EUR 533

Mouse Anti-Spiramycin monoclonal antibody, clone SPM

CABT-L3062-1mg 1 mg
EUR 1313

Mouse Anti-Kitasamycin monoclonal antibody, clone KSM

CABT-L3063-100ug 100 ug
EUR 533

Mouse Anti-Kitasamycin monoclonal antibody, clone KSM

CABT-L3063-1mg 1 mg
EUR 1313

Mouse Anti-Halofuginone monoclonal antibody, clone HAL

CABT-L3065-100ug 100 ug
EUR 533

Mouse Anti-Halofuginone monoclonal antibody, clone HAL

CABT-L3065-1mg 1 mg
EUR 1313

Mouse Anti-Aminophylline monoclonal antibody, clone APL

CABT-L3066-100ug 100 ug
EUR 533

Mouse Anti-Aminophylline monoclonal antibody, clone APL

CABT-L3066-1mg 1 mg
EUR 1313

Mouse Anti-Tiamulin monoclonal antibody, clone TML

CABT-L3067-100ug 100 ug
EUR 533

Mouse Anti-Tiamulin monoclonal antibody, clone TML

CABT-L3067-1mg 1 mg
EUR 1313

Mouse Anti-Flavomycin monoclonal antibody, clone FVM

CABT-L3068-100ug 100 ug
EUR 533

Mouse Anti-Flavomycin monoclonal antibody, clone FVM

CABT-L3068-1mg 1 mg
EUR 1313

Mouse Anti-Furanacrylate monoclonal antibody, clone FAA

CABT-L3069-100ug 100 ug
EUR 533

Mouse Anti-Furanacrylate monoclonal antibody, clone FAA

CABT-L3069-1mg 1 mg
EUR 1313

Mouse Anti-Thiamethoxam monoclonal antibody, clone TMO

CABT-L3071-100ug 100 ug
EUR 533

Mouse Anti-Thiamethoxam monoclonal antibody, clone TMO

CABT-L3071-1mg 1 mg
EUR 1313

Mouse Anti-Nifursol monoclonal antibody, clone NFS

CABT-L3079-100ug 100 ug
EUR 533

Mouse Anti-Nifursol monoclonal antibody, clone NFS

CABT-L3079-1mg 1 mg
EUR 1313

Mouse Anti-Azaperone monoclonal antibody, clone AZP

CABT-L3081-100ug 100 ug
EUR 533

Mouse Anti-Azaperone monoclonal antibody, clone AZP

CABT-L3081-1mg 1 mg
EUR 1313

Mouse Anti-Chlorpromazine monoclonal antibody, clone CPZ

CABT-L3082-100ug 100 ug
EUR 533

Mouse Anti-Chlorpromazine monoclonal antibody, clone CPZ

CABT-L3082-1mg 1 mg
EUR 1313

Mouse Anti-Procaine monoclonal antibody, clone PRC

CABT-L3083-100ug 100 ug
EUR 533

Mouse Anti-Procaine monoclonal antibody, clone PRC

CABT-L3083-1mg 1 mg
EUR 1313

Mouse Anti-Meloxicam monoclonal antibody, clone MLX

CABT-L3084-100ug 100 ug
EUR 533

Mouse Anti-Meloxicam monoclonal antibody, clone MLX

CABT-L3084-1mg 1 mg
EUR 1313

Mouse Anti-Tadalafil monoclonal antibody, clone TD

CABT-L3085-100ug 100 ug
EUR 533

Mouse Anti-Tadalafil monoclonal antibody, clone TD

CABT-L3085-1mg 1 mg
EUR 1313

Mouse Anti-Benzopyrene monoclonal antibody, clone BaP

CABT-L3086-100ug 100 ug
EUR 533

Mouse Anti-Benzopyrene monoclonal antibody, clone BaP

CABT-L3086-1mg 1 mg
EUR 1313

Mouse Anti-Capsaicin monoclonal antibody, clone CPS

CABT-L3087-100ug 100 ug
EUR 533

Mouse Anti-Capsaicin monoclonal antibody, clone CPS

CABT-L3087-1mg 1 mg
EUR 1313

Mouse Anti-Cimaterol monoclonal antibody, clone CIM

CABT-L3088-100ug 100 ug
EUR 533

Mouse Anti-Cimaterol monoclonal antibody, clone CIM

CABT-L3088-1mg 1 mg
EUR 1313

Mouse Anti-Tetrodotoxin monoclonal antibody, clone TTX

CABT-L3089-100ug 100 ug
EUR 533

Mouse Anti-Tetrodotoxin monoclonal antibody, clone TTX

CABT-L3089-1mg 1 mg
EUR 1313

Mouse Anti-Clothianidin monoclonal antibody, clone CTD

CABT-L3091-100ug 100 ug
EUR 533

Mouse Anti-Clothianidin monoclonal antibody, clone CTD

CABT-L3091-1mg 1 mg
EUR 1313

Mouse Anti-Sibutramine monoclonal antibody, clone SBTM

CABT-L3093-100ug 100 ug
EUR 533

Mouse Anti-Sibutramine monoclonal antibody, clone SBTM

CABT-L3093-1mg 1 mg
EUR 1313

Mouse Anti-Indometacin monoclonal antibody, clone IDM

CABT-L3094-100ug 100 ug
EUR 533

Mouse Anti-Indometacin monoclonal antibody, clone IDM

CABT-L3094-1mg 1 mg
EUR 1313

Mouse Anti-Berberine monoclonal antibody, clone BBR

CABT-L3096-100ug 100 ug
EUR 533

Mouse Anti-Berberine monoclonal antibody, clone BBR

CABT-L3096-1mg 1 mg
EUR 1313

Mouse Anti-Calicheamicin monoclonal antibody, clone C2H0

CABT-L3107 100 uL
EUR 1937

Mouse Anti-Duocarmycin monoclonal antibody, clone  F22B2

CABT-L3109 100 uL
EUR 1646

Mouse Anti-Amanitin monoclonal antibody, clone I4F2

CABT-L3113 100 uL
EUR 1937

Mouse Anti-SN38 monoclonal antibody, clone 20G22B0E7

CABT-L3115 100 uL
EUR 1646

Mouse Anti-ADV monoclonal antibody, clone 23H07

CABT-L3195 1 mg
EUR 819

Mouse Anti-ICHV monoclonal antibody, clone B21E25

CABT-L3197 1 mg
EUR 819

Mouse Anti-MH monoclonal antibody, clone 9C24

CABT-L3198 1 mg
EUR 819

Mouse Anti-CCV monoclonal antibody, clone B83,4

CABT-L3199 1 mg
EUR 819

Mouse Anti-Dioxin monoclonal antibody, clone DXN

CABT-L4232-100ug 100 ug
EUR 533

Mouse Anti-Dioxin monoclonal antibody, clone DXN

CABT-L4232-1mg 1 mg
EUR 1313

Mouse Anti-Amantadine monoclonal antibody, clone AM

CABT-L4233-100ug 100 ug
EUR 533

Mouse Anti-Amantadine monoclonal antibody, clone AM

CABT-L4233-1mg 1 mg
EUR 1313

Mouse Anti-Aminobenzimidazole monoclonal antibody, clone ABI

CABT-L4235-100ug 100 ug
EUR 533

Mouse Anti-Aminobenzimidazole monoclonal antibody, clone ABI

CABT-L4235-1mg 1 mg
EUR 1313

Mouse Anti-Carbadox monoclonal antibody, clone CBD

CABT-L4236-100ug 100 ug
EUR 533

Mouse Anti-Carbadox monoclonal antibody, clone CBD

CABT-L4236-1mg 1 mg
EUR 1313

Mouse Anti-Rifampicin monoclonal antibody, clone RFP

CABT-L4237-100ug 100 ug
EUR 533

Mouse Anti-Rifampicin monoclonal antibody, clone RFP

CABT-L4237-1mg 1 mg
EUR 1313

Mouse Anti-Praziquantel monoclonal antibody, clone PZQ

CABT-L4238-100ug 100 ug
EUR 533

Mouse Anti-Praziquantel monoclonal antibody, clone PZQ

CABT-L4238-1mg 1 mg
EUR 1313

Mouse Anti-Robenidine monoclonal antibody, clone RBD

CABT-L4239-100ug 100 ug
EUR 533

Mouse Anti-Robenidine monoclonal antibody, clone RBD

CABT-L4239-1mg 1 mg
EUR 1313

Mouse Anti-Dinitolmide monoclonal antibody, clone DNT

CABT-L4240-100ug 100 ug
EUR 533

Mouse Anti-Dinitolmide monoclonal antibody, clone DNT

CABT-L4240-1mg 1 mg
EUR 1313

Mouse Anti-Ethopabate monoclonal antibody, clone EPB

CABT-L4241-100ug 100 ug
EUR 533

Mouse Anti-Ethopabate monoclonal antibody, clone EPB

CABT-L4241-1mg 1 mg
EUR 1313

Mouse Anti-Imidocarb monoclonal antibody, clone IMC

CABT-L4243-100ug 100 ug
EUR 533

Mouse Anti-Imidocarb monoclonal antibody, clone IMC

CABT-L4243-1mg 1 mg
EUR 1313

Mouse Anti-Triazophos monoclonal antibody, clone TZP

CABT-L4244-100ug 100 ug
EUR 533

Mouse Anti-Triazophos monoclonal antibody, clone TZP

CABT-L4244-1mg 1 mg
EUR 1313

Mouse Anti-Isoprocarb monoclonal antibody, clone IPC

CABT-L4245-100ug 100 ug
EUR 533

Mouse Anti-Isoprocarb monoclonal antibody, clone IPC

CABT-L4245-1mg 1 mg
EUR 1313

Mouse Anti-Pyrimethanil monoclonal antibody, clone PMT

CABT-L4246-100ug 100 ug
EUR 533

Mouse Anti-Pyrimethanil monoclonal antibody, clone PMT

CABT-L4246-1mg 1 mg
EUR 1313

Mouse Anti-Picoxystrobin monoclonal antibody, clone POS

CABT-L4247-100ug 100 ug
EUR 533

Mouse Anti-Picoxystrobin monoclonal antibody, clone POS

CABT-L4247-1mg 1 mg
EUR 1313

Mouse Anti-Carbamazepine monoclonal antibody, clone CMZ

CABT-L4248-100ug 100 ug
EUR 533

Mouse Anti-Carbamazepine monoclonal antibody, clone CMZ

CABT-L4248-1mg 1 mg
EUR 1313

Mouse Anti-Carazolol monoclonal antibody, clone CZL

CABT-L4249-100ug 100 ug
EUR 533

Mouse Anti-Carazolol monoclonal antibody, clone CZL

CABT-L4249-1mg 1 mg
EUR 1313

Mouse Anti-Glibenclamide monoclonal antibody, clone GBC

CABT-L4250-100ug 100 ug
EUR 533

Mouse Anti-Glibenclamide monoclonal antibody, clone GBC

CABT-L4250-1mg 1 mg
EUR 1313
This demonstrates that TMEJ can perform upstream of the Vacation junction resolvases to guard cells from lack of heterozygosity. Our work argues that Pol θ can thus compensate for the lack of the Holliday junction resolvases by utilizing homologous recombination intermediates, suppressing mitotic crossing over and preserving the genomic stability of cells.