Natural Zeitgebers Under Temperate Conditions Cannot Compensate for the Loss of a Functional Circadian Clock in Timing of a Vital Behavior in Drosophila
The adaptive significance of adjusting behavioral actions to the best time of the day appears apparent. Laboratory research implicated an essential position of circadian clocks in behavioral timing and rhythmicity. But, latest research on clock-mutant animals questioned this significance below extra naturalistic settings, as numerous clock mutants confirmed almost regular diel exercise rhythms below seminatural zeitgeber circumstances.
We right here report proof that correct timing of eclosion, a significant habits of the fruit fly Drosophila melanogaster, requires a purposeful molecular clock below quasi-natural circumstances. In distinction to wild-type flies, interval01 mutants with a faulty molecular clock confirmed impaired rhythmicity and gating in a temperate setting even within the presence of a full complement of abiotic zeitgebers. Though interval01 mutants nonetheless eclosed throughout a sure time window in the course of the day, this time window was a lot broader and loosely outlined, and rhythmicity was decrease or misplaced as categorized by numerous statistical measures. Furthermore, peak eclosion time turned extra inclined to variable day-to-day modifications of sunshine.
In distinction, flies with impaired peptidergic interclock signaling (Pdf01 and han5304 PDF receptor mutants) eclosed largely rhythmically with regular gate sizes, much like wild-type controls. Our outcomes recommend that the presence of pure zeitgebers isn’t adequate, and a purposeful molecular clock is required to induce steady temporal eclosion patterns in flies below temperate circumstances with appreciable day-to-day variation in gentle depth and temperature. Temperate zeitgebers are, nonetheless, adequate to functionally rescue a lack of PDF-mediated clock-internal and -output signaling.
Nanda-Hamner Curves Present Large Latitudinal Variation however No Circadian Elements in Drosophila Montana Photoperiodism
Insect species with a large distribution provide an important alternative to hint latitudinal variation within the photoperiodic regulation of traits essential in copy and stress tolerances. We measured this variation within the photoperiodic time-measuring system underlying reproductive diapause in Drosophila montana, utilizing a Nanda-Hamner (NH) protocol. Not one of the research strains confirmed diel rhythmicity in feminine diapause proportions below a continuing day size (12 h) and ranging night time lengths in photoperiods starting from 16 to 84 h at 16°C. Within the northernmost strains (above 55°N), almost all females entered diapause below all photoperiods and about half of them even in steady darkness, whereas the females of the southern strains confirmed excessive diapause proportions solely within the circadian 24 h photoperiod.
Important correlation between the strains’ imply diapause proportions in ≥ 24 h photoperiods and important day size (CDL; half of the females enter diapause) suggests at the least partial causal connection between the traits. Apparently, females of the northern strains entered diapause even in ≤ 24 h photoperiods, the place the night time size was shorter than their important night time size (24 h – CDL), however the place the females skilled a better variety of Gentle:Darkish cycles than in 24 h photoperiods.
NH experiments, carried out on the management and choice strains in our earlier choice experiment, and accomplished right here, gave comparable outcomes and confirmed that choice for shorter, southern-type CDL decreases feminine diapausing fee in non-circadian photoperiods. Total, our research exhibits that D. montana females measure night time size quantitatively, that the photoperiodic counter could play a distinguished however barely totally different position in further quick and further lengthy photoperiods and that northern strains present excessive stability towards perturbations within the photoperiod size and within the presence of LD cycles. These options are finest defined by the quantitative variations of the damped exterior coincidence mannequin.
Interaction between intercourse willpower cascade and main signaling pathways throughout Drosophila eye improvement: Views for future analysis
Understanding molecular mechanisms of sexually dimorphic organ progress is a elementary downside of developmental biology. Current quantitative research confirmed that the Drosophila compound eye is a handy mannequin to review the willpower of the ultimate organ measurement. In Drosophila, females have bigger eyes than males and that is evident even after correction for the bigger physique measurement. Furthermore, feminine eyes embody extra ommatidia (photosensitive items) than male eyes and this distinction is specified on the third larval instar within the eye primordia referred to as eye imaginal discs. This will likely end in totally different visible capabilities between the 2 sexes and have behavioral penalties.
Regardless of rising proof on the genetic bases of eye measurement variation between totally different Drosophila species and strains, mechanisms accountable for within-species sexual dimorphism nonetheless stay elusive. Right here, we focus on a presumptive crosstalk between the intercourse willpower cascade and main signaling pathways throughout dimorphic eye improvement. Male- and female-specific isoforms of Doublesex (Dsx) protein are identified to regulate sex-specific differentiation within the somatic tissues. Nonetheless, no information on Dsx perform throughout eye disc progress and patterning are presently accessible.
Remarkably, Intercourse deadly (Sxl), the intercourse willpower change protein, was proven to straight have an effect on Hedgehog (Hh) and Notch (N) signaling within the Drosophila wing disc. The similarity of signaling pathways concerned within the wing and eye disc progress means that Sxl is perhaps built-in into regulation of eye improvement. Dsx position within the eye disc requires additional investigation. We focus on presently accessible information on sex-biased gene expression within the Drosophila eye and spotlight views for future research.
DNA polymerase theta suppresses mitotic crossing over
Polymerase theta-mediated finish becoming a member of (TMEJ) is a chromosome break restore pathway that is ready to rescue the lethality related to the lack of proteins concerned in early steps in homologous recombination (e.g., BRCA1/2). That is because of the capacity of polymerase theta (Pol θ) to make use of resected, 3′ single stranded DNA tails to restore chromosome breaks. These resected DNA tails are additionally the beginning substrate for homologous recombination. Nonetheless, it stays unknown if TMEJ can compensate for the lack of proteins concerned in additional downstream steps throughout homologous recombination. Right here we present that the Holliday junction resolvases SLX4 and GEN1 are required for viability within the absence of Pol θ in Drosophila melanogaster, and lack of all three proteins ends in excessive ranges of apoptosis.
Flies poor in Pol θ and SLX4 are extraordinarily delicate to DNA damaging brokers, and mammalian cells require both Pol θ or SLX4 to outlive. Our outcomes recommend that TMEJ and Holliday junction formation/decision share a standard DNA substrate, seemingly a homologous recombination intermediate, that when left unrepaired results in cell demise. One main consequence of Holliday junction decision by SLX4 and GEN1 is cancer-causing lack of heterozygosity as a consequence of mitotic crossing over. We measured mitotic crossovers in flies after a Cas9-induced chromosome break, and noticed that this mutagenic type of restore is elevated within the absence of Pol θ.
 (M02), Clone: 3E11) Monoclonal SSX4 Antibody (monoclonal) (M02), Clone: 3E11 |
|
APR10252G |
Leading Biology |
0.1mg |
EUR 484 |
|
Description: A Monoclonal antibody against Human SSX4 (monoclonal) (M02). The antibodies are raised in mouse and are from clone 3E11. This antibody is applicable in WB and IF, E |
 (M01), Clone: 3E11) Monoclonal ATP7B Antibody (monoclonal) (M01), Clone: 3E11 |
|
APG02168G |
Leading Biology |
0.1mg |
EUR 484 |
|
Description: A Monoclonal antibody against Human ATP7B (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3E11. This antibody is applicable in WB, E |
 (M01), Clone: 3E11) Monoclonal HIP1R Antibody (monoclonal) (M01), Clone: 3E11 |
|
APR12375G |
Leading Biology |
0.05mg |
EUR 484 |
|
Description: A Monoclonal antibody against Human HIP1R (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3E11. This antibody is applicable in WB, E |
 (M01), Clone: 3E11) Monoclonal TCF4 Antibody (monoclonal) (M01), Clone: 3E11 |
|
APR14413G |
Leading Biology |
0.1mg |
EUR 484 |
|
Description: A Monoclonal antibody against Human TCF4 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3E11. This antibody is applicable in WB and IF |
 (M08), Clone: 3E11) Monoclonal COPB Antibody (monoclonal) (M08), Clone: 3E11 |
|
APR15551G |
Leading Biology |
0.1mg |
EUR 484 |
|
Description: A Monoclonal antibody against Human COPB (monoclonal) (M08). The antibodies are raised in mouse and are from clone 3E11. This antibody is applicable in E |
 (M09), Clone: 3E11) Monoclonal FBL Antibody (monoclonal) (M09), Clone: 3E11 |
|
APR15927G |
Leading Biology |
0.1mg |
EUR 484 |
|
Description: A Monoclonal antibody against Human FBL (monoclonal) (M09). The antibodies are raised in mouse and are from clone 3E11. This antibody is applicable in E |
 (M01), Clone: 3E11-F6) Monoclonal PDLIM5 Antibody (monoclonal) (M01), Clone: 3E11-F6 |
|
APR12791G |
Leading Biology |
0.1mg |
EUR 484 |
|
Description: A Monoclonal antibody against Human PDLIM5 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3E11-F6. This antibody is applicable in WB and IF, E |
) Anti Mummichog Vitellogenin Monoclonal Antibody (Clone No. 3E11) |
|
KH005 |
Sceti |
|
EUR 544 |
|
Description: The Anti Mummichog Vitellogenin Monoclonal Antibody (Clone No. 3E11) is available in Europe and for worldwide shipping via Gentaur. |
) Anti-Twist (3E11) |
|
YF-MA10977 |
Abfrontier |
100 ug |
EUR 363 |
|
Description: Mouse monoclonal to Twist |
) Anti-cvHSP (3E11) |
|
YF-MA11450 |
Abfrontier |
100 ug |
EUR 363 |
|
Description: Mouse monoclonal to cvHSP |
) Anti-AKT1 (3E11) |
|
YF-MA11876 |
Abfrontier |
100 ug |
EUR 363 |
|
Description: Mouse monoclonal to AKT1 |
) Anti-OSGIN2 (3E11) |
|
YF-MA12209 |
Abfrontier |
100 ug |
EUR 363 |
|
Description: Mouse monoclonal to OSGIN2 |
) Anti-FMRP (3E11) |
|
YF-MA13101 |
Abfrontier |
100 ug |
EUR 363 |
|
Description: Mouse monoclonal to FMRP |
) Anti-MCM3 (3E11) |
|
YF-MA14152 |
Abfrontier |
100 ug |
EUR 363 |
|
Description: Mouse monoclonal to MCM3 |
) Anti-NHLH2 (3E11) |
|
YF-MA14458 |
Abfrontier |
100 ug |
EUR 363 |
|
Description: Mouse monoclonal to NHLH2 |
) Anti-POMC (3E11) |
|
YF-MA14807 |
Abfrontier |
100 ug |
EUR 363 |
|
Description: Mouse monoclonal to POMC |
) Anti-RPL23A (3E11) |
|
YF-MA15244 |
Abfrontier |
100 ug |
EUR 363 |
|
Description: Mouse monoclonal to RPL23A |
) Anti-Psoriasin (3E11) |
|
YF-MA15314 |
Abfrontier |
50 ug |
EUR 363 |
|
Description: Mouse monoclonal to Psoriasin |
Anti-Psoriasin (3E11) |
|
YF-MA15315 |
Abfrontier |
200 ul |
EUR 363 |
|
Description: Mouse monoclonal to Psoriasin |
) Anti-Osteopontin (3E11) |
|
YF-MA15581 |
Abfrontier |
100 ug |
EUR 363 |
|
Description: Mouse monoclonal to Osteopontin |
) Anti-TCF2 (3E11) |
|
YF-MA15765 |
Abfrontier |
100 ug |
EUR 363 |
|
Description: Mouse monoclonal to TCF2 |
) Anti-KLF10 (3E11) |
|
YF-MA15849 |
Abfrontier |
100 ug |
EUR 363 |
|
Description: Mouse monoclonal to KLF10 |
) Anti-ZNF187 (3E11) |
|
YF-MA16192 |
Abfrontier |
100 ug |
EUR 363 |
|
Description: Mouse monoclonal to ZNF187 |
) Anti-CER1 (3E11) |
|
YF-MA16795 |
Abfrontier |
100 ug |
EUR 363 |
|
Description: Mouse monoclonal to CER1 |
) Anti-TIP30 (3E11) |
|
YF-MA17378 |
Abfrontier |
100 ug |
EUR 363 |
|
Description: Mouse monoclonal to TIP30 |
) Anti-CCRK (3E11) |
|
YF-MA17926 |
Abfrontier |
100 ug |
EUR 363 |
|
Description: Mouse monoclonal to CCRK |
) Anti-BTBD1 (3E11) |
|
YF-MA18595 |
Abfrontier |
100 ug |
EUR 363 |
|
Description: Mouse monoclonal to BTBD1 |
) Anti-ALS2CR2 (3E11) |
|
YF-MA18781 |
Abfrontier |
100 ug |
EUR 363 |
|
Description: Mouse monoclonal to ALS2CR2 |
) Anti-SPG (3E11) |
|
YF-MA18829 |
Abfrontier |
50 ug |
EUR 363 |
|
Description: Mouse monoclonal to SPG |
) Anti-MRPS36 (3E11) |
|
YF-MA19657 |
Abfrontier |
100 ug |
EUR 363 |
|
Description: Mouse monoclonal to MRPS36 |
) Anti-MPO (3E11) |
|
YF-MA20367 |
Abfrontier |
100 ug |
EUR 363 |
|
Description: Mouse monoclonal to MPO |
) Anti-ARFGEF1 (3E11) |
|
YF-MA20498 |
Abfrontier |
100 ug |
EUR 363 |
|
Description: Mouse monoclonal to ARFGEF1 |
) anti-HDAC3 (3E11) |
|
LF-MA10133 |
Abfrontier |
100 ug |
EUR 363 |
|
Description: Mouse monoclonal to HDAC3 |
) Anti-ORC2 (3E11-1G5) |
|
YF-MA10652 |
Abfrontier |
100 ug |
EUR 363 |
|
Description: Mouse monoclonal to ORC2 |
) Anti-PDLIM5 (3E11-F6) |
|
YF-MA11302 |
Abfrontier |
100 ug |
EUR 363 |
|
Description: Mouse monoclonal to PDLIM5 |
) Anti-IkB beta (3E11) |
|
YF-MA14442 |
Abfrontier |
100 ug |
EUR 363 |
|
Description: Mouse monoclonal to IkB beta |
) anti-Progesteron Receptor (3E11) |
|
LF-MA10230 |
Abfrontier |
100 ug |
EUR 363 |
|
Description: Mouse monoclonal to Progesteron Receptor |
Mouse Monoclonal Antibody [Clone KU729], Clone: KU729) Monoclonal Ku (p70/p80)Mouse Monoclonal Antibody [Clone KU729], Clone: KU729 |
|
AMM00210G |
Leading Biology |
0.5ml |
EUR 484 |
|
Description: A Monoclonal antibody against Human Ku (p70/p80)Mouse Monoclonal [Clone KU729]. The antibodies are raised in Mouse and are from clone KU729. This antibody is applicable in IF, FC |
 Monoclonal Mouse Bmi1 Antibody, Clone: 353CT22.4.4 |
|
AMM02383G |
Leading Biology |
0.1ml |
EUR 484 |
|
Description: A Monoclonal antibody against Human Mouse Bmi1. The antibodies are raised in Mouse and are from clone 353CT22.4.4. This antibody is applicable in WB, E |
 Monoclonal mouse Lplunc1 Antibody, Clone: 4H2 |
|
APR08492G |
Leading Biology |
0.1ml |
EUR 528 |
|
Description: A Monoclonal antibody against Human mouse Lplunc1. The antibodies are raised in Mouse and are from clone 4H2. This antibody is applicable in WB and IHC, FC, ICC, E |
 Monoclonal mouse Lplunc1 Antibody, Clone: 1F11E3 |
|
APR08493G |
Leading Biology |
0.1ml |
EUR 528 |
|
Description: A Monoclonal antibody against Human mouse Lplunc1. The antibodies are raised in Mouse and are from clone 1F11E3. This antibody is applicable in WB, E |
 Monoclonal mouse Splunc2 Antibody, Clone: 1F12 |
|
APR07136G |
Leading Biology |
0.1ml |
EUR 528 |
|
Description: A Monoclonal antibody against Human mouse Splunc2. The antibodies are raised in Mouse and are from clone 1F12. This antibody is applicable in WB and IHC, FC, ICC, E |
, Clone: CD28.2) Monoclonal CD28 FITC Monoclonal Antibody (Clone CD28.2), Clone: CD28.2 |
|
AMM00025G |
Leading Biology |
0.05mg |
EUR 396 |
|
Description: A Monoclonal antibody against Human CD28 FITC Monoclonal (Clone CD28.2). The antibodies are raised in Mouse and are from clone CD28.2. This antibody is applicable in FC |
, Clone: 3.9) Monoclonal CD11c FITC Monoclonal Antibody (Clone 3.9), Clone: 3.9 |
|
APR15331G |
Leading Biology |
50 tests |
EUR 484 |
|
Description: A Monoclonal antibody against Human CD11c FITC Monoclonal (Clone 3.9). The antibodies are raised in Mouse and are from clone 3.9. This antibody is applicable in FC |
, Clone: Clone # 8G3G10) Monoclonal NGFR Antibody (Clone # 8G3G10), Clone: Clone # 8G3G10 |
|
AMM06686G |
Leading Biology |
0.1ml |
EUR 484 |
|
Description: A Monoclonal antibody against Human NGFR (Clone # 8G3G10). The antibodies are raised in Mouse and are from clone Clone # 8G3G10. This antibody is applicable in WB and IF, FC |
, Clone: Clone IMG48M7C7) Monoclonal S100A8 Antibody (Clone IMG48M7C7), Clone: Clone IMG48M7C7 |
|
AMM00015G |
Leading Biology |
0.1mg |
EUR 528 |
|
Description: A Monoclonal antibody against Human S100A8 (Clone IMG48M7C7). The antibodies are raised in Mouse and are from clone Clone IMG48M7C7. This antibody is applicable in WB and IHC |
, Clone: Clone # 275CT1) Monoclonal PDGFR Antibody (Clone # 275CT1), Clone: Clone # 275CT1 |
|
AMM00020G |
Leading Biology |
0.05ml |
EUR 484 |
|
Description: A Monoclonal antibody against Human PDGFR (Clone # 275CT1). The antibodies are raised in Mouse and are from clone Clone # 275CT1. This antibody is applicable in WB |
, Clone: 1H4) Monoclonal CST3 Antibody (monoclonal), Clone: 1H4 |
|
AMM03425G |
Leading Biology |
0.1mg |
EUR 484 |
|
Description: A Monoclonal antibody against Human CST3 (monoclonal). The antibodies are raised in Mouse and are from clone 1H4. This antibody is applicable in WB |
, Clone: 2E11) Monoclonal TNFSF18 Antibody (monoclonal), Clone: 2E11 |
|
AMM04221G |
Leading Biology |
0.1mg |
EUR 484 |
|
Description: A Monoclonal antibody against Human TNFSF18 (monoclonal). The antibodies are raised in mouse and are from clone 2E11. This antibody is applicable in WB, E |
, Clone: 4G7) Monoclonal FTL Antibody (monoclonal), Clone: 4G7 |
|
AMM04622G |
Leading Biology |
0.1mg |
EUR 484 |
|
Description: A Monoclonal antibody against Human FTL (monoclonal). The antibodies are raised in Mouse and are from clone 4G7. This antibody is applicable in WB, E |
 Mouse Anti-Mouse TIGIT Monoclonal antibody, clone 1G9 |
|
CABT-L4298-1mg |
Creative Diagnostics |
1 mg |
EUR 897 |
Mouse Anti-Mouse TIGIT Monoclonal antibody, clone 1G9 |
|
CABT-L4298-5mg |
Creative Diagnostics |
5 mg |
EUR 2405 |
 Mouse Anti-Mouse CD22 Monoclonal antibody, clone Cy34.1 |
|
CABT-L4309-1mg |
Creative Diagnostics |
1 mg |
EUR 897 |
Mouse Anti-Mouse CD22 Monoclonal antibody, clone Cy34.1 |
|
CABT-L4309-5mg |
Creative Diagnostics |
5 mg |
EUR 2405 |
 Mouse Anti-Mouse NK1.1 Monoclonal antibody, clone PK136 |
|
CABT-L4348-1mg |
Creative Diagnostics |
1 mg |
EUR 897 |
Mouse Anti-Mouse NK1.1 Monoclonal antibody, clone PK136 |
|
CABT-L4348-5mg |
Creative Diagnostics |
5 mg |
EUR 2405 |
 Mouse Anti-Mouse CD45.2 Monoclonal antibody, clone 104.2 |
|
CABT-L4528-1mg |
Creative Diagnostics |
1 mg |
EUR 897 |
Mouse Anti-Mouse CD45.2 Monoclonal antibody, clone 104.2 |
|
CABT-L4528-5mg |
Creative Diagnostics |
5 mg |
EUR 2405 |
 Mouse Anti-Albendazole monoclonal antibody, clone ABZ2 |
|
CABT-L3042-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Albendazole monoclonal antibody, clone ABZ2 |
|
CABT-L3042-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Fluoroquinolones monoclonal antibody, clone FK2 |
|
CABT-L3046-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Fluoroquinolones monoclonal antibody, clone FK2 |
|
CABT-L3046-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Fluoroquinolones monoclonal antibody, clone FK3 |
|
CABT-L3047-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Fluoroquinolones monoclonal antibody, clone FK3 |
|
CABT-L3047-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Cyproheptadine monoclonal antibody, clone CHD |
|
CABT-L3052-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Cyproheptadine monoclonal antibody, clone CHD |
|
CABT-L3052-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Clonidine monoclonal antibody, clone CLD |
|
CABT-L3053-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Clonidine monoclonal antibody, clone CLD |
|
CABT-L3053-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Diaveridine monoclonal antibody, clone DVD |
|
CABT-L3055-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Diaveridine monoclonal antibody, clone DVD |
|
CABT-L3055-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Ormetoprim monoclonal antibody, clone OMP |
|
CABT-L3056-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Ormetoprim monoclonal antibody, clone OMP |
|
CABT-L3056-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Clindamycin monoclonal antibody, clone CDM |
|
CABT-L3057-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Clindamycin monoclonal antibody, clone CDM |
|
CABT-L3057-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Azithromycin monoclonal antibody, clone ATM |
|
CABT-L3058-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Azithromycin monoclonal antibody, clone ATM |
|
CABT-L3058-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Roxithromycin monoclonal antibody, clone RTM |
|
CABT-L3059-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Roxithromycin monoclonal antibody, clone RTM |
|
CABT-L3059-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Clarithromycin monoclonal antibody, clone CTM |
|
CABT-L3060-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Clarithromycin monoclonal antibody, clone CTM |
|
CABT-L3060-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Spiramycin monoclonal antibody, clone SPM |
|
CABT-L3062-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Spiramycin monoclonal antibody, clone SPM |
|
CABT-L3062-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Kitasamycin monoclonal antibody, clone KSM |
|
CABT-L3063-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Kitasamycin monoclonal antibody, clone KSM |
|
CABT-L3063-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Halofuginone monoclonal antibody, clone HAL |
|
CABT-L3065-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Halofuginone monoclonal antibody, clone HAL |
|
CABT-L3065-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Aminophylline monoclonal antibody, clone APL |
|
CABT-L3066-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Aminophylline monoclonal antibody, clone APL |
|
CABT-L3066-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Tiamulin monoclonal antibody, clone TML |
|
CABT-L3067-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Tiamulin monoclonal antibody, clone TML |
|
CABT-L3067-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Flavomycin monoclonal antibody, clone FVM |
|
CABT-L3068-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Flavomycin monoclonal antibody, clone FVM |
|
CABT-L3068-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Furanacrylate monoclonal antibody, clone FAA |
|
CABT-L3069-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Furanacrylate monoclonal antibody, clone FAA |
|
CABT-L3069-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Thiamethoxam monoclonal antibody, clone TMO |
|
CABT-L3071-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Thiamethoxam monoclonal antibody, clone TMO |
|
CABT-L3071-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Nifursol monoclonal antibody, clone NFS |
|
CABT-L3079-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Nifursol monoclonal antibody, clone NFS |
|
CABT-L3079-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Azaperone monoclonal antibody, clone AZP |
|
CABT-L3081-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Azaperone monoclonal antibody, clone AZP |
|
CABT-L3081-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Chlorpromazine monoclonal antibody, clone CPZ |
|
CABT-L3082-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Chlorpromazine monoclonal antibody, clone CPZ |
|
CABT-L3082-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Procaine monoclonal antibody, clone PRC |
|
CABT-L3083-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Procaine monoclonal antibody, clone PRC |
|
CABT-L3083-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Meloxicam monoclonal antibody, clone MLX |
|
CABT-L3084-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Meloxicam monoclonal antibody, clone MLX |
|
CABT-L3084-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Tadalafil monoclonal antibody, clone TD |
|
CABT-L3085-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Tadalafil monoclonal antibody, clone TD |
|
CABT-L3085-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Benzopyrene monoclonal antibody, clone BaP |
|
CABT-L3086-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Benzopyrene monoclonal antibody, clone BaP |
|
CABT-L3086-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Capsaicin monoclonal antibody, clone CPS |
|
CABT-L3087-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Capsaicin monoclonal antibody, clone CPS |
|
CABT-L3087-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Cimaterol monoclonal antibody, clone CIM |
|
CABT-L3088-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Cimaterol monoclonal antibody, clone CIM |
|
CABT-L3088-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Tetrodotoxin monoclonal antibody, clone TTX |
|
CABT-L3089-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Tetrodotoxin monoclonal antibody, clone TTX |
|
CABT-L3089-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Clothianidin monoclonal antibody, clone CTD |
|
CABT-L3091-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Clothianidin monoclonal antibody, clone CTD |
|
CABT-L3091-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Sibutramine monoclonal antibody, clone SBTM |
|
CABT-L3093-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Sibutramine monoclonal antibody, clone SBTM |
|
CABT-L3093-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Indometacin monoclonal antibody, clone IDM |
|
CABT-L3094-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Indometacin monoclonal antibody, clone IDM |
|
CABT-L3094-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Berberine monoclonal antibody, clone BBR |
|
CABT-L3096-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Berberine monoclonal antibody, clone BBR |
|
CABT-L3096-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Calicheamicin monoclonal antibody, clone C2H0 |
|
CABT-L3107 |
Creative Diagnostics |
100 uL |
EUR 1937 |
 Mouse Anti-Duocarmycin monoclonal antibody, clone F22B2 |
|
CABT-L3109 |
Creative Diagnostics |
100 uL |
EUR 1646 |
 Mouse Anti-SN38 monoclonal antibody, clone 20G22B0E7 |
|
CABT-L3115 |
Creative Diagnostics |
100 uL |
EUR 1646 |
 Mouse Anti-Dioxin monoclonal antibody, clone DXN |
|
CABT-L4232-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
 Mouse Anti-Amantadine monoclonal antibody, clone AM |
|
CABT-L4233-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Amantadine monoclonal antibody, clone AM |
|
CABT-L4233-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Aminobenzimidazole monoclonal antibody, clone ABI |
|
CABT-L4235-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Aminobenzimidazole monoclonal antibody, clone ABI |
|
CABT-L4235-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Carbadox monoclonal antibody, clone CBD |
|
CABT-L4236-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Carbadox monoclonal antibody, clone CBD |
|
CABT-L4236-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Rifampicin monoclonal antibody, clone RFP |
|
CABT-L4237-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Rifampicin monoclonal antibody, clone RFP |
|
CABT-L4237-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Praziquantel monoclonal antibody, clone PZQ |
|
CABT-L4238-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Praziquantel monoclonal antibody, clone PZQ |
|
CABT-L4238-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Robenidine monoclonal antibody, clone RBD |
|
CABT-L4239-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Robenidine monoclonal antibody, clone RBD |
|
CABT-L4239-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Dinitolmide monoclonal antibody, clone DNT |
|
CABT-L4240-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Dinitolmide monoclonal antibody, clone DNT |
|
CABT-L4240-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Ethopabate monoclonal antibody, clone EPB |
|
CABT-L4241-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Ethopabate monoclonal antibody, clone EPB |
|
CABT-L4241-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Imidocarb monoclonal antibody, clone IMC |
|
CABT-L4243-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Imidocarb monoclonal antibody, clone IMC |
|
CABT-L4243-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Triazophos monoclonal antibody, clone TZP |
|
CABT-L4244-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Triazophos monoclonal antibody, clone TZP |
|
CABT-L4244-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Isoprocarb monoclonal antibody, clone IPC |
|
CABT-L4245-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Isoprocarb monoclonal antibody, clone IPC |
|
CABT-L4245-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Pyrimethanil monoclonal antibody, clone PMT |
|
CABT-L4246-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Pyrimethanil monoclonal antibody, clone PMT |
|
CABT-L4246-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Picoxystrobin monoclonal antibody, clone POS |
|
CABT-L4247-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Picoxystrobin monoclonal antibody, clone POS |
|
CABT-L4247-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Carbamazepine monoclonal antibody, clone CMZ |
|
CABT-L4248-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Carbamazepine monoclonal antibody, clone CMZ |
|
CABT-L4248-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Carazolol monoclonal antibody, clone CZL |
|
CABT-L4249-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Carazolol monoclonal antibody, clone CZL |
|
CABT-L4249-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
 Mouse Anti-Glibenclamide monoclonal antibody, clone GBC |
|
CABT-L4250-100ug |
Creative Diagnostics |
100 ug |
EUR 533 |
Mouse Anti-Glibenclamide monoclonal antibody, clone GBC |
|
CABT-L4250-1mg |
Creative Diagnostics |
1 mg |
EUR 1313 |
This demonstrates that TMEJ can perform upstream of the Vacation junction resolvases to guard cells from lack of heterozygosity. Our work argues that Pol θ can thus compensate for the lack of the Holliday junction resolvases by utilizing homologous recombination intermediates, suppressing mitotic crossing over and preserving the genomic stability of cells.
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