Category: Yeast

dHNF4 regulates lipid homeostasis and oogenesis in Drosophila melanogaster

The fly genome comprises a single ortholog of the evolutionarily conserved transcription issue hepatocyte nuclear issue 4 (HNF4), a broadly and constitutively expressed member of the nuclear receptor superfamily. Like its mammalian orthologs, Drosophila HNF4 (dHNF4) acts as a important regulator of fatty acid and glucose homeostasis. Due to its function in power storage and catabolism, the

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Daily temperature cycles prolong lifespan and have sex-specific effects on peripheral clock gene expression in Drosophila melanogaster

Circadian rhythms optimize well being by coordinating the timing of physiological processes to match predictable every day environmental challenges. The circadian rhythm of physique temperature is regarded as an vital modulator of molecular clocks in peripheral tissues, however how every day temperature cycles influence physiological perform is unclear. Right here, we examined the impact of

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