Mad dephosphorylation at the nuclear pore is essential for asymmetric stem cell division
Stem cells divide asymmetrically to generate a stem cell and a differentiating daughter cell. But, it stays poorly understood how a stem cell and a differentiating daughter cell can obtain distinct ranges of area of interest sign and thus purchase completely different cell fates (self-renewal versus differentiation), regardless of being adjoining to one another and thus seemingly uncovered to comparable ranges of area of interest signaling. Within the Drosophila ovary, germline stem cells (GSCs) are maintained by brief vary bone morphogenetic protein (BMP) signaling; the BMP ligands activate a receptor that phosphorylates the downstream molecule moms in opposition to decapentaplegic (Mad).
Phosphorylated Mad (pMad) accumulates within the GSC nucleus and prompts the stem cell transcription program. Right here, we exhibit that pMad is extremely concentrated within the nucleus of the GSC, whereas it rapidly decreases within the nucleus of the differentiating daughter cell, the precystoblast (preCB), earlier than the completion of cytokinesis. We present {that a} identified Mad phosphatase, Dullard (Dd), is required for the uneven partitioning of pMad. Our mathematical modeling recapitulates the excessive sensitivity of the ratio of pMad ranges to the Mad phosphatase exercise and explains how the asymmetry arises in a shared cytoplasm. Collectively, these research reveal a mechanism for breaking the symmetry of daughter cells throughout uneven stem cell division.
Suppression of mixture and amyloid formation by a novel intrinsically disordered area in metazoan Hsp110 chaperones
Molecular chaperones preserve proteostasis by making certain the correct folding of polypeptides. Lack of proteostasis has been linked to quite a few neurodegenerative problems together with Alzheimer’s, Parkinson’s, and Huntington’s illness. Hsp110 is expounded to the canonical Hsp70 class of protein folding molecular chaperones and interacts with Hsp70 as a nucleotide trade issue (NEF). Along with its NEF exercise, Hsp110 possesses an Hsp70-like substrate binding area (SBD) whose organic roles stay undefined. Earlier work in Drosophila melanogaster has implicated the only real Hsp110 gene (Hsc70cb) in proteinopathic neurodegeneration.
We hypothesize that along with its function as an Hsp70 NEF, Drosophila Hsp110 might perform as a protecting protein “holdase”, stopping the aggregation of unfolded polypeptides through the SBD-b subdomain. We exhibit for the primary time that Drosophila Hsp110 successfully prevents aggregation of the mannequin substrate citrate synthase. We additionally report the invention of a redundant and heretofore unknown potent holdase capability in a 138 amino-acid area of Hsp110 carboxyl-terminal to each SBD-b and SBD-α (henceforth known as the C-terminal extension).
This sequence is extremely conserved in metazoan Hsp110 genes, fully absent from fungal representatives, and is computationally predicted to include an intrinsically disordered area (IDR). We exhibit that this IDR sequence inside the human Hsp110s, Apg-1 and Hsp105α, inhibits the formation of amyloid Aβ-42 and α-synuclein fibrils in vitro however can not mediate fibril disassembly. Collectively these findings set up capability for metazoan Hsp110 chaperones to suppress each common protein aggregation and amyloidogenesis, elevating the potential for exploitation of this IDR for therapeutic profit.
Digital screening identifies a novel piperazine-based insect juvenile hormone agonist
Juvenile hormone (JH) agonists represent a subclass of insect development regulators and play necessary roles in insect pest administration. On this work, a multi-step digital screening program was executed to search out novel JH agonists. A database of 5 million purchasable compounds was sequentially processed with three computational filters: (i) form and chemical similarity as in comparison with identified JH-active compounds; (ii) molecular docking simulations in opposition to a Drosophila JH receptor, methoprene-tolerant; and (iii) free vitality calculation of ligand-receptor binding utilizing a modified MM/PBSA (molecular mechanics/Poisson-Boltzmann floor space) protocol.
The 11 candidates that handed the three filters have been evaluated in a luciferase reporter assay, resulting in the identification of a success compound that accommodates a piperazine ring system (EC50=870 nM). This compound is structurally dissimilar to identified JH agonists and synthetically straightforward to entry; due to this fact, it’s a promising place to begin for additional construction optimization.
Transporter-mediated ecdysteroid trafficking throughout cell membranes: A novel goal for insect development regulators
Ecdysteroids are a category of steroid hormones in arthropods that management molting and metamorphosis via interplay with intracellular nuclear receptors. In distinction to the in depth literature describing their biosynthetic pathways and signaling parts, little has been identified about how these hormones are touring into and out of the cells via lipid bilayers of the cell membranes. Just lately, a collection of research performed within the fruit fly Drosophila melanogaster revealed that membrane transporters have vital features in trafficking ecdysteroids throughout cell membranes, difficult the classical easy diffusion mannequin of steroid hormone transport. Right here we summarize latest advances in our understanding of membrane transporters concerned in ecdysteroid signaling in Drosophila, with explicit give attention to Ecdysone Importer (EcI) that’s concerned in ecdysteroid uptake in peripheral tissues. We then talk about the potential benefit of EcI blockers as a novel pest administration instrument as in comparison with classical insect development regulators.
Glial Hedgehog signalling and lipid metabolism regulate neural stem cell proliferation in Drosophila
The ultimate dimension and performance of the grownup central nervous system (CNS) are decided by neuronal lineages generated by neural stem cells (NSCs) within the creating mind. In Drosophila, NSCs known as neuroblasts (NBs) reside inside a specialised microenvironment known as the glial area of interest. Right here, we discover non-autonomous glial regulation of NB proliferation. We present that lipid droplets (LDs) which reside inside the glial area of interest are carefully related to the signalling molecule Hedgehog (Hh).
ELISA kit for Mouse Slit2 (Slit Homolog 2) |
ELK2103 |
ELK Biotech |
1 plate of 96 wells |
EUR 518.4 |
|
Description: A sandwich ELISA kit for detection of Slit Homolog 2 from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
Mouse Slit Homolog 2 Protein ELISA Kit |
IMSSLIT2KT |
Innovative research |
each |
EUR 702 |
|
Description: Mouse Slit Homolog 2 Protein ELISA Kit |
Mouse Slit homolog 2 protein ELISA Kit |
MBS763653-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 3900 |
Mouse Slit homolog 2 protein ELISA Kit |
MBS763653-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 340 |
Mouse Slit homolog 2 protein ELISA Kit |
MBS763653-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 2045 |
Mouse Slit homolog 2 protein ELISA Kit |
MBS763653-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 455 |
Mouse Slit Homolog 2 Protein ELISA Kit |
MBS8420880-1Kit |
MyBiosource |
1Kit |
EUR 755 |
Mouse Slit Homolog 2 Protein ELISA Kit |
MBS8420880-5x1Kit |
MyBiosource |
5x1Kit |
EUR 3455 |
Mouse Slit homolog 2 protein ELISA Kit |
MBS2886077-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 4080 |
Mouse Slit homolog 2 protein ELISA Kit |
MBS2886077-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 390 |
Mouse Slit homolog 2 protein ELISA Kit |
MBS2886077-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 2220 |
Mouse Slit homolog 2 protein ELISA Kit |
MBS2886077-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 520 |
Mouse Slit2/ Slit homolog 2 protein ELISA Kit |
E1378Mo |
Sunlong |
1 Kit |
EUR 543 |
|
Mouse Slit homolog 2 protein (SLIT2) ELISA Kit |
EK7240 |
SAB |
96Т |
EUR 799 |
|
Mouse Slit homolog 2 protein (SLIT2) ELISA Kit |
AE18234MO-48Tests |
Abebio |
48 Tests |
EUR 325 |
|
Description: Mouse (Mus musculus) |
Mouse Slit homolog 2 protein (SLIT2) ELISA Kit |
AE18234MO-96Tests |
Abebio |
96 Tests |
EUR 610 |
|
Description: Mouse (Mus musculus) |
Mouse Slit homolog 2 protein (SLIT2) ELISA Kit |
AE18234MO-48T |
Abebio |
48T |
EUR 325 |
|
Description: Mouse (Mus musculus) |
Mouse Slit homolog 2 protein (SLIT2) ELISA Kit |
AE18234MO-96T |
Abebio |
96T |
EUR 610 |
|
Description: Mouse (Mus musculus) |
Mouse Slit homolog 2 protein, Slit2 ELISA KIT |
ELI-02346m |
Nova Lifetech |
96tests |
EUR 736 |
Mouse Slit2( Slit homolog 2 protein) ELISA Kit |
EM0434 |
FN Test |
96T |
EUR 681.12 |
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.094 ng/ml |
Mouse Slit homolog 2 protein (SLIT2) ELISA Kit |
RK07143 |
Abclonal |
96T |
EUR 280 |
Mouse Slit2 / Slit homolog 2 protein ELISA Kit |
E0672m |
EIAab |
96T |
EUR 776 |
Mouse Slit homolog 2 protein (SLIT2) ELISA Kit |
MBS2802039-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6255 |
Mouse Slit homolog 2 protein (SLIT2) ELISA Kit |
MBS2802039-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 445 |
Mouse Slit homolog 2 protein (SLIT2) ELISA Kit |
MBS2802039-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3290 |
Mouse Slit homolog 2 protein (SLIT2) ELISA Kit |
MBS2802039-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 730 |
ELISA kit for Rat Slit homolog 2 protein (SLIT2) |
KTE100240-48T |
Abbkine |
48T |
EUR 398.4 |
|
Description: Quantitative sandwich ELISA for measuring Rat Slit homolog 2 protein (SLIT2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Rat Slit homolog 2 protein (SLIT2) |
KTE100240-5platesof96wells |
Abbkine |
5 plates of 96 wells |
EUR 2538 |
|
Description: Quantitative sandwich ELISA for measuring Rat Slit homolog 2 protein (SLIT2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Rat Slit homolog 2 protein (SLIT2) |
KTE100240-96T |
Abbkine |
96T |
EUR 646.8 |
|
Description: Quantitative sandwich ELISA for measuring Rat Slit homolog 2 protein (SLIT2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human Slit homolog 2 protein (SLIT2) |
KTE60581-5platesof96wells |
Abbkine |
5 plates of 96 wells |
EUR 2538 |
|
Description: Quantitative sandwich ELISA for measuring Human Slit homolog 2 protein (SLIT2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Mouse Slit3 (Slit Homolog 3) |
ELK7762 |
ELK Biotech |
1 plate of 96 wells |
EUR 518.4 |
|
Description: A sandwich ELISA kit for detection of Slit Homolog 3 from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
ELISA kit for Mouse Slit1 (Slit Homolog 1) |
ELK6408 |
ELK Biotech |
1 plate of 96 wells |
EUR 518.4 |
|
Description: A sandwich ELISA kit for detection of Slit Homolog 1 from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
Mouse Slit homolog 3 protein (SLIT3) ELISA Kit |
EK7237 |
SAB |
96Т |
EUR 799 |
|
Mouse Slit homolog 1 protein (SLIT1) ELISA Kit |
EK7243 |
SAB |
96Т |
EUR 799 |
|
Mouse Slit homolog 3 protein (SLIT3) ELISA Kit |
AE18231MO-48Tests |
Abebio |
48 Tests |
EUR 325 |
|
Description: Mouse (Mus musculus) |
Mouse Slit homolog 3 protein (SLIT3) ELISA Kit |
AE18231MO-96Tests |
Abebio |
96 Tests |
EUR 610 |
|
Description: Mouse (Mus musculus) |
Mouse Slit homolog 1 protein (SLIT1) ELISA Kit |
AE18239MO-48Tests |
Abebio |
48 Tests |
EUR 325 |
|
Description: Mouse (Mus musculus) |
Mouse Slit homolog 1 protein (SLIT1) ELISA Kit |
AE18239MO-96Tests |
Abebio |
96 Tests |
EUR 610 |
|
Description: Mouse (Mus musculus) |
Mouse Slit homolog 3 protein (SLIT3) ELISA Kit |
AE18231MO-48T |
Abebio |
48T |
EUR 325 |
|
Description: Mouse (Mus musculus) |
Mouse Slit homolog 3 protein (SLIT3) ELISA Kit |
AE18231MO-96T |
Abebio |
96T |
EUR 610 |
|
Description: Mouse (Mus musculus) |
Mouse Slit homolog 1 protein (SLIT1) ELISA Kit |
AE18239MO-48T |
Abebio |
48T |
EUR 325 |
|
Description: Mouse (Mus musculus) |
Mouse Slit homolog 1 protein (SLIT1) ELISA Kit |
AE18239MO-96T |
Abebio |
96T |
EUR 610 |
|
Description: Mouse (Mus musculus) |
Mouse Slit homolog 3 protein, Slit3 ELISA KIT |
ELI-18165m |
Nova Lifetech |
96tests |
EUR 736 |
Mouse Slit homolog 1 protein, Slit1 ELISA KIT |
ELI-18718m |
Nova Lifetech |
96tests |
EUR 736 |
Mouse Slit homolog 3 protein (SLIT3) ELISA Kit |
KTE70415-48T |
Abbkine |
48T |
EUR 339 |
|
Description: This Mouse Slit homolog 3 protein (SLIT3) ELISA Kit employs a two-site sandwich ELISA to quantitate SLIT3. |
Mouse Slit homolog 3 protein (SLIT3) ELISA Kit |
KTE70415-96T |
Abbkine |
96T |
EUR 589 |
|
Description: This Mouse Slit homolog 3 protein (SLIT3) ELISA Kit employs a two-site sandwich ELISA to quantitate SLIT3. |
Mouse Slit homolog 3 protein (SLIT3) ELISA Kit |
KTE70415-96T5 |
Abbkine |
96 T×5 |
EUR 2629 |
Description: This Mouse Slit homolog 3 protein (SLIT3) ELISA Kit employs a two-site sandwich ELISA to quantitate SLIT3. |
Mouse Slit homolog 3 protein (SLIT3) ELISA Kit |
KTE70415-96T50 |
Abbkine |
96 T×50 |
EUR 24569 |
Description: This Mouse Slit homolog 3 protein (SLIT3) ELISA Kit employs a two-site sandwich ELISA to quantitate SLIT3. |
Mouse Slit3 / Slit homolog 3 protein ELISA Kit |
E10185m |
EIAab |
96T |
EUR 776 |
Mouse Slit homolog 1 protein, SLIT1 ELISA Kit |
MBS9317914-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Mouse Slit homolog 1 protein, SLIT1 ELISA Kit |
MBS9317914-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Mouse Slit homolog 1 protein, SLIT1 ELISA Kit |
MBS9317914-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Mouse Slit homolog 1 protein, SLIT1 ELISA Kit |
MBS9317914-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
Mouse Slit3/Slit homolog 3 protein ELISA Kit |
MBS2903882-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 4080 |
Mouse Slit3/Slit homolog 3 protein ELISA Kit |
MBS2903882-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 390 |
Mouse Slit3/Slit homolog 3 protein ELISA Kit |
MBS2903882-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 2220 |
Mouse Slit3/Slit homolog 3 protein ELISA Kit |
MBS2903882-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 520 |
Mouse Slit Homolog 3 Protein (SLIT3) ELISA Kit |
MBS9717023-48Tests |
MyBiosource |
48Tests |
EUR 340 |
Mouse Slit Homolog 3 Protein (SLIT3) ELISA Kit |
MBS9717023-5x96Tests |
MyBiosource |
5x96Tests |
EUR 1820 |
Mouse Slit Homolog 3 Protein (SLIT3) ELISA Kit |
MBS9717023-96Tests |
MyBiosource |
96Tests |
EUR 500 |
ELISA kit for Rat Slit homolog 3 protein (SLIT3) |
KTE100239-48T |
Abbkine |
48T |
EUR 398.4 |
|
Description: Quantitative sandwich ELISA for measuring Rat Slit homolog 3 protein (SLIT3) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Rat Slit homolog 3 protein (SLIT3) |
KTE100239-5platesof96wells |
Abbkine |
5 plates of 96 wells |
EUR 2538 |
|
Description: Quantitative sandwich ELISA for measuring Rat Slit homolog 3 protein (SLIT3) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Rat Slit homolog 3 protein (SLIT3) |
KTE100239-96T |
Abbkine |
96T |
EUR 646.8 |
|
Description: Quantitative sandwich ELISA for measuring Rat Slit homolog 3 protein (SLIT3) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Rat Slit homolog 1 protein (SLIT1) |
KTE100241-48T |
Abbkine |
48T |
EUR 398.4 |
|
Description: Quantitative sandwich ELISA for measuring Rat Slit homolog 1 protein (SLIT1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Rat Slit homolog 1 protein (SLIT1) |
KTE100241-5platesof96wells |
Abbkine |
5 plates of 96 wells |
EUR 2538 |
|
Description: Quantitative sandwich ELISA for measuring Rat Slit homolog 1 protein (SLIT1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Rat Slit homolog 1 protein (SLIT1) |
KTE100241-96T |
Abbkine |
96T |
EUR 646.8 |
|
Description: Quantitative sandwich ELISA for measuring Rat Slit homolog 1 protein (SLIT1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human Slit homolog 3 protein (SLIT3) |
KTE60580-5platesof96wells |
Abbkine |
5 plates of 96 wells |
EUR 2538 |
|
Description: Quantitative sandwich ELISA for measuring Human Slit homolog 3 protein (SLIT3) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human Slit homolog 1 protein (SLIT1) |
KTE60582-5platesof96wells |
Abbkine |
5 plates of 96 wells |
EUR 2538 |
|
Description: Quantitative sandwich ELISA for measuring Human Slit homolog 1 protein (SLIT1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
CLIA kit for Mouse Slit2 (Slit Homolog 2) |
E-CL-M0508 |
Elabscience Biotech |
1 plate of 96 wells |
EUR 700.8 |
|
Description: A sandwich CLIA kit for quantitative measurement of Mouse Slit2 (Slit Homolog 2) in samples from Serum, Plasma, Cell supernatant |
Mouse Slit Homolog 2 ELISA kit |
E01A25235 |
BlueGene |
96T |
EUR 700 |
Description: ELISA |
Mouse Slit Homolog 2 ELISA kit |
E03S0112-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Mouse Slit Homolog 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Slit Homolog 2 ELISA kit |
E03S0112-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Mouse Slit Homolog 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Slit Homolog 2 ELISA kit |
E03S0112-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Mouse Slit Homolog 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Slit Homolog 2 ELISA Kit |
MBS042427-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Mouse Slit Homolog 2 ELISA Kit |
MBS042427-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Mouse Slit Homolog 2 ELISA Kit |
MBS042427-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Mouse Slit Homolog 2 ELISA Kit |
MBS042427-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
Mouse Slit Homolog 2 ELISA Kit |
MBS721386-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 5685 |
Mouse Slit Homolog 2 ELISA Kit |
MBS721386-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 485 |
Mouse Slit Homolog 2 ELISA Kit |
MBS721386-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3020 |
Mouse Slit Homolog 2 ELISA Kit |
MBS721386-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 690 |
ELISA Kit for Slit Homolog 2 (Slit2) |
SEA672Hu |
Cloud-Clone |
96Т |
EUR 630 |
|
ELISA Kit for Slit Homolog 2 (Slit2) |
SEA672Mu |
Cloud-Clone |
96Т |
EUR 648 |
|
ELISA Kit for Slit Homolog 2 (Slit2) |
SEA672Ra |
Cloud-Clone |
96Т |
EUR 684 |
|
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
abx051309-96tests |
Abbexa |
96 tests |
EUR 943.2 |
|
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
abx254788-96tests |
Abbexa |
96 tests |
EUR 801.6 |
|
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
abx576307-96tests |
Abbexa |
96 tests |
EUR 801.6 |
|
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
20-abx154689 |
Abbexa |
-
Ask for price
-
Ask for price
-
Ask for price
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
DLR-Slit2-Mu |
DL Develop |
96T |
EUR 432 |
|
Description: serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
DLR-Slit2-Mu-48T |
DL Develop |
48T |
EUR 586.8 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Slit Homolog 2 (Slit2) in samples from serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
DLR-Slit2-Mu-96T |
DL Develop |
96T |
EUR 762 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Slit Homolog 2 (Slit2) in samples from serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
DL-Slit2-Mu |
DL Develop |
96T |
EUR 412 |
|
Description: serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
EK16660 |
SAB |
96Т |
EUR 768 |
|
Mouse Slit2(Slit Homolog 2) ELISA Kit |
ELK2103-48T |
ELK Biotech |
48T |
Ask for price |
|
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse Slit2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse Slit2. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse Slit2, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse Slit2 in the samples is then determined by comparing the OD of the samples to the standard curve. |
Mouse Slit2(Slit Homolog 2) ELISA Kit |
ELK2103-96T |
ELK Biotech |
96T |
Ask for price |
|
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse Slit2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse Slit2. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse Slit2, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse Slit2 in the samples is then determined by comparing the OD of the samples to the standard curve. |
Mouse Slit Homolog 2 (Slit2)ELISA Kit |
NSL1284m |
Sunlong |
96 Test |
EUR 528 |
|
Mouse Slit2(Slit Homolog 2) ELISA Kit |
RE1524M-48wells |
Reed Biotech |
48 wells |
EUR 116.55 |
|
Mouse Slit2(Slit Homolog 2) ELISA Kit |
RE1524M-96wells |
Reed Biotech |
96 wells |
EUR 161.55 |
|
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
RDR-Slit2-Mu-48T |
Reddot Biotech |
48T |
EUR 443.42 |
|
Description: serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
RDR-Slit2-Mu-48Tests |
Reddot Biotech |
48 Tests |
EUR 613.2 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
RDR-Slit2-Mu-96T |
Reddot Biotech |
96T |
EUR 633.47 |
|
Description: serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
RDR-Slit2-Mu-96Tests |
Reddot Biotech |
96 Tests |
EUR 850.8 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
RD-Slit2-Mu-48T |
Reddot Biotech |
48T |
EUR 422.3 |
|
Description: serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
RD-Slit2-Mu-48Tests |
Reddot Biotech |
48 Tests |
EUR 586.8 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
RD-Slit2-Mu-96T |
Reddot Biotech |
96T |
EUR 603.3 |
|
Description: serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
RD-Slit2-Mu-96Tests |
Reddot Biotech |
96 Tests |
EUR 812.4 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
SEA672Mu-10x96wellstestplate |
Cloud-Clone |
10x96-wells test plate |
EUR 5269.39 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Slit Homolog 2 (Slit2) in serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
SEA672Mu-1x48wellstestplate |
Cloud-Clone |
1x48-wells test plate |
EUR 539.12 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Slit Homolog 2 (Slit2) in serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
SEA672Mu-1x96wellstestplate |
Cloud-Clone |
1x96-wells test plate |
EUR 718.75 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Slit Homolog 2 (Slit2) in serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
SEA672Mu-5x96wellstestplate |
Cloud-Clone |
5x96-wells test plate |
EUR 2874.38 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Slit Homolog 2 (Slit2) in serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
4-SEA672Mu |
Cloud-Clone |
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- 10 plates of 96 wells
- 5 plates of 96 wells
- 1 plate of 96 wells
|
|
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Slit Homolog 2 (Slit2) in samples from serum, plasma, tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
abx051309-100g |
Abbexa |
100 µg |
Ask for price |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
abx051309-10g |
Abbexa |
10 µg |
EUR 587.5 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
abx051309-50g |
Abbexa |
50 µg |
Ask for price |
Mouse Slit2 (Slit Homolog 2) ELISA Kit |
MBS8801104-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 3130 |
Mouse Slit2 (Slit Homolog 2) ELISA Kit |
MBS8801104-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 350 |
Mouse Slit2 (Slit Homolog 2) ELISA Kit |
MBS8801104-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 1710 |
Mouse Slit2 (Slit Homolog 2) ELISA Kit |
MBS8801104-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 445 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
MBS2023517-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 4995 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
MBS2023517-24StripWells |
MyBiosource |
24-Strip-Wells |
EUR 345 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
MBS2023517-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 510 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
MBS2023517-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 2735 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
MBS2023517-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 680 |
Mouse Slit2 (Slit Homolog 2) ELISA Kit |
MBS2508823-10x96Tests |
MyBiosource |
10x96Tests |
EUR 4060 |
Mouse Slit2 (Slit Homolog 2) ELISA Kit |
MBS2508823-24Tests |
MyBiosource |
24Tests |
EUR 265 |
Mouse Slit2 (Slit Homolog 2) ELISA Kit |
MBS2508823-48Tests |
MyBiosource |
48Tests |
EUR 450 |
Mouse Slit2 (Slit Homolog 2) ELISA Kit |
MBS2508823-5x96Tests |
MyBiosource |
5x96Tests |
EUR 2265 |
Mouse Slit2 (Slit Homolog 2) ELISA Kit |
MBS2508823-96Tests |
MyBiosource |
96Tests |
EUR 535 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
MBS4502538-10x96Tests |
MyBiosource |
10x96Tests |
EUR 4965 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
MBS4502538-48Tests |
MyBiosource |
48Tests |
EUR 435 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
MBS4502538-5x96Tests |
MyBiosource |
5x96Tests |
EUR 2550 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
MBS4502538-96Test |
MyBiosource |
96Test |
EUR 575 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
MBS455198-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 4800 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
MBS455198-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 420 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
MBS455198-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 2465 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
MBS455198-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 550 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
MBS264138-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 3290 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
MBS264138-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 295 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
MBS264138-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 1800 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
MBS264138-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 450 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
MBS2702252-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 2905 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
MBS2702252-24StripWells |
MyBiosource |
24-Strip-Wells |
EUR 240 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
MBS2702252-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 320 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
MBS2702252-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 1515 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
MBS2702252-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 390 |
Mouse Slit Homolog 2 (Slit2) ELISA Kit |
EIA06347m |
Enlibio |
each |
EUR 480 |
Mouse Slit Homolog 2 (Slit2) Protein |
20-abx069121 |
Abbexa |
-
Ask for price
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-
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|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Mouse Slit Homolog 2 (Slit2) Protein |
20-abx168430 |
Abbexa |
-
Ask for price
-
Ask for price
-
Ask for price
-
Ask for price
-
Ask for price
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Mouse Slit Homolog 2 (Slit2) Protein |
abx168430-100l |
Abbexa |
100 µl |
EUR 225 |
Mouse Slit Homolog 2 (Slit2) Protein |
abx168430-1ml |
Abbexa |
1 ml |
EUR 587.5 |
Mouse Slit Homolog 2 (Slit2) Protein |
abx168430-200l |
Abbexa |
200 µl |
EUR 412.5 |
Mouse Slit Homolog 2 (Slit2) Protein |
abx069121-100g |
Abbexa |
100 µg |
EUR 587.5 |
Mouse Slit Homolog 2 (Slit2) Protein |
abx069121-1g |
Abbexa |
1 µg |
EUR 225 |
Mouse Slit Homolog 2 (Slit2) Protein |
abx069121-5g |
Abbexa |
5 µg |
EUR 412.5 |
Rat Slit homolog 2 protein ELISA Kit |
MBS2882758-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 4000 |
Rat Slit homolog 2 protein ELISA Kit |
MBS2882758-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 395 |
Rat Slit homolog 2 protein ELISA Kit |
MBS2882758-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 2185 |
Rat Slit homolog 2 protein ELISA Kit |
MBS2882758-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 520 |
ELISA kit for Rat SLIT2 (Slit Homolog 2) |
E-EL-R0886 |
Elabscience Biotech |
1 plate of 96 wells |
EUR 640.8 |
|
Description: A sandwich ELISA kit for quantitative measurement of Rat SLIT2 (Slit Homolog 2) in samples from Serum, Plasma, Cell supernatant |
ELISA kit for Rat Slit2 (Slit Homolog 2) |
ELK2972 |
ELK Biotech |
1 plate of 96 wells |
EUR 518.4 |
|
Description: A sandwich ELISA kit for detection of Slit Homolog 2 from Rat in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
Beneath physiological situations, cortex glial Hh is autonomously required to maintain area of interest chamber formation. Upon FGF-mediated cortex glial overgrowth, glial Hh non-autonomously prompts Hh signalling within the NBs, which in flip disrupts NB cell cycle development and its potential to provide neurons. Glial Hh’s potential to sign to NB is additional modulated by lipid storage regulator lipid storage droplet-2 (Lsd-2) and de novo lipogenesis gene fatty acid synthase 1 (Fasn1). Collectively, our knowledge recommend that glial-derived Hh modified by lipid metabolism mechanisms can have an effect on the neighbouring NB’s potential to proliferate and produce neurons.
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