Transcriptomic analysis of feminizing somatic stem cells in the Drosophila testis reveal putative downstream effectors of the transcription factor Chinmo
The most effective examples of sexual dimorphism is the event and performance of the gonads, ovaries and testes, which produce sex-specific gametes, oocytes and spermatids, respectively. The event of those specialised germ cells requires sex-matched somatic assist cells. The sexual id of somatic gonadal cells is specified throughout growth and have to be actively maintained throughout maturity. We beforehand confirmed that the transcription issue Chinmo is required to make sure the male sexual id of somatic assist cells within the Drosophila melanogaster testis.
Lack of chinmo from male somatic gonadal cells leads to feminization: they remodel from squamous to epithelial-like cells that resemble somatic cells within the feminine gonad however fail to correctly ensheath the male germline, inflicting infertility. To determine potential goal genes of Chinmo, we purified somatic cells poor for chinmo from the grownup Drosophila testis and carried out next-generation sequencing to check their transcriptome to that of management somatic cells. Bioinformatics revealed 304 and 1,549 differentially upregulated and downregulated genes, respectively, upon lack of chinmo in early somatic cells. Utilizing a mixture of strategies, we validated a number of differentially expressed genes. These information units will likely be helpful assets to the neighborhood.
Non-steroidal inhibitors of Drosophila melanogaster steroidogenic glutathione S-transferase Noppera-bo
Insect progress regulators (IGRs) could be developed by elucidating the molecular mechanisms of insect-specific organic occasions. As a result of insect molting, and metamorphosis are managed by ecdysteroids, their biosynthetic pathways can function targets for IGR growth. The glutathione S-transferase Noppera-bo (Nobo), which is conserved in dipteran and lepidopteran species, performs a vital position in ecdysteroid biosynthesis. Our earlier research utilizing 17β-estradiol as a molecular probe revealed that Asp113 of Drosophila melanogaster Nobo (DmNobo) is crucial for its organic perform.
Nevertheless, to develop IGRs with a higher Nobo inhibitory exercise than 17β-estradiol, additional structural info is warranted. Right here, we report 5 novel non-steroidal DmNobo inhibitors. Evaluation of crystal buildings of complexes revealed that DmNobo binds these inhibitors in an Asp113-independent method. Amongst amino acid residues on the substrate-recognition web site, conformation of conserved Phe39 was dynamically altered upon inhibitor binding. Due to this fact, these inhibitors can function seed compounds for IGR growth.
Kinome-Large RNAi Display Uncovers Function of Ballchen in Upkeep of Gene Activation by Trithorax Group in Drosophila
Polycomb group (PcG) and trithorax group (trxG) proteins are evolutionary conserved elements that contribute to cell destiny dedication and upkeep of mobile identities throughout growth of multicellular organisms. The PcG maintains heritable patterns of gene silencing whereas trxG acts as anti-silencing elements by conserving activation of cell sort particular genes. Genetic and molecular evaluation has revealed intensive particulars about how totally different PcG and trxG complexes antagonize one another to keep up cell fates, nonetheless, the mobile signaling elements that contribute to the preservation of gene expression by PcG/trxG stay elusive. Right here, we report an ex vivo kinome-wide RNAi display in Drosophila geared toward figuring out cell signaling genes that facilitate trxG in counteracting PcG mediated repression. From the checklist of trxG candidates, Ballchen (BALL), a histone kinase recognized to phosphorylate histone H2A at threonine 119 (H2AT119p), was characterised as a trxG regulator.
The ball mutant displays robust genetic interactions with Polycomb (Computer) and trithorax (trx) mutants and lack of BALL impacts expression of trxG goal genes. BALL co-localizes with Trithorax on chromatin and depletion of BALL leads to elevated H2AK118 ubiquitination, a histone mark central to PcG mediated gene silencing. Furthermore, BALL was discovered to considerably affiliate with recognized TRX binding websites throughout the genome. Genome huge distribution of BALL additionally overlaps with H3K4me3 and H3K27ac at actively transcribed genes. We suggest that BALL mediated signaling positively contributes to the upkeep of gene activation by trxG in counteracting the repressive impact of PcG.
Towards a Consensus within the Repertoire of Hemocytes Recognized in Drosophila
The catalog of the Drosophila immune cells was till lately restricted to 3 main cell varieties, based mostly on morphology, perform and few molecular markers. Three latest single cell research spotlight the presence of a number of subgroups, revealing a big variety within the molecular signature of the larval immune cells. Since these research depend on considerably totally different experimental and analytical approaches, we right here evaluate the datasets and determine eight frequent, sturdy subgroups related to distinct features comparable to proliferation, immune response, phagocytosis or secretion. Related comparative analyses with datasets from totally different levels and tissues disclose the presence of larval immune cells resembling embryonic hemocyte progenitors and the expression of particular properties in larval immune cells related to peripheral tissues.
The S6k/4E-BP mediated progress selling sub-pathway of insulin signalling cascade is crucial to limit pathogenesis of poly(Q) issues in Drosophila
Human neurodegenerative polyglutamine [poly(Q)] issues, comparable to Huntington’s illness (HD) and spinocerebellar ataxias (SCA), are characterised by an irregular growth of CAG repeats within the affected gene. The mutated proteins misfold and combination to kind inclusion our bodies that sequester essential elements concerned in mobile transcription, progress, stress and autophagic response and different important features. The insulin signalling pathway has been demonstrated as a serious modifier and a possible drug goal to ameliorate the poly(Q) mediated neurotoxicity in numerous mannequin programs. Insulin signalling cascade harbours a number of downstream sub-pathways, that are synergistically concerned in discharging indispensable organic features comparable to progress and proliferation, metabolism, autophagy, regulation of cell loss of life pathways and so forth.
Therefore, it’s troublesome to conclude whether or not the mitigation of poly(Q) neurotoxicity is an accumulative end result of the insulin cascade, or the results of a particular sub-pathway. For the primary time, we report that the ligand binding area of insulin receptor mediated downstream progress selling sub-pathway performs the pivotal position in working the rescue occasion. We present that the expansion selling exercise of insulin cascade is crucial to reduce the abundance of inclusion our bodies, to limit neurodegeneration, and to revive the mobile transcriptional stability.
Recombinant Drosophila melanogaster Bursicon (burs) |
RPC23763-20ug |
Biomatik Corporation |
20ug |
EUR 448.1 |
Recombinant Drosophila melanogaster Bursicon(burs) |
AP73151 |
SAB |
each |
Ask for price |
|
Recombinant Drosophila melanogaster Bursicon(burs) |
AP71620 |
SAB |
1mg |
EUR 2826 |
|
Recombinant Drosophila melanogaster Bursicon (burs) |
CSB-EP894207DLU |
Cusabio |
4824 mg |
Ask for price |
Recombinant Drosophila melanogaster Bursicon (burs) |
CSB-YP894207DLU |
Cusabio |
6746 mg |
Ask for price |
Recombinant Drosophila melanogaster GEO11329p1 (ITP) |
RPC28452-100ug |
Biomatik Corporation |
100ug |
EUR 1931.2 |
Recombinant Drosophila melanogaster GEO11329p1 (ITP) |
RPC28452-20ug |
Biomatik Corporation |
20ug |
EUR 726 |
Recombinant Drosophila melanogaster GEO11329p1 (ITP) |
RPC28453-100ug |
Biomatik Corporation |
100ug |
EUR 1931.2 |
Recombinant Drosophila melanogaster GEO11329p1 (ITP) |
RPC28453-20ug |
Biomatik Corporation |
20ug |
EUR 726 |
Recombinant Drosophila melanogaster GEO11329p1 (ITP) |
CSB-MP3350DLU |
Cusabio |
7152 mg |
Ask for price |
Recombinant Drosophila melanogaster GEO11329p1 (ITP) |
CSB-MP3350DLUh6 |
Cusabio |
7153 mg |
Ask for price |
Recombinant Drosophila melanogaster Protein shifted (shf) |
CSB-EP893839DLUb1 |
Cusabio |
9227 mg |
Ask for price |
GAGA-POZ Drosophila Melanogaster Recombinant Protein |
PROTQ08605 |
BosterBio |
Regular: 50ug |
EUR 380.4 |
Description: GAGA-POZ Drosophila Melanogaster Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 130 amino acids & having a molecular mass of 14 kDa. |
Recombinant Drosophila melanogaster Pro-resilin (resilin) ,partial |
RPC27353-100ug |
Biomatik Corporation |
100ug |
EUR 801.9 |
Recombinant Drosophila melanogaster Pro-resilin (resilin) ,partial |
RPC27353-1mg |
Biomatik Corporation |
1mg |
EUR 2885.2 |
Recombinant Drosophila melanogaster Pro-resilin (resilin) ,partial |
RPC27353-20ug |
Biomatik Corporation |
20ug |
EUR 448.1 |
Recombinant Drosophila melanogaster Pro-resilin (resilin), partial |
CSB-EP892693DLU |
Cusabio |
6998 mg |
Ask for price |
Recombinant Drosophila melanogaster Protein bottleneck(bnk) |
AP73870 |
SAB |
1mg |
EUR 2826 |
|
Recombinant Drosophila melanogaster Neuroglian (Nrg), partial |
CSB-BP322617DLU |
Cusabio |
9759 mg |
Ask for price |
Recombinant Drosophila melanogaster Protein bottleneck (bnk) |
CSB-EP328169DLU |
Cusabio |
2949 mg |
Ask for price |
Recombinant Drosophila melanogaster Thioredoxin-2(Trx-2) |
AP73856 |
SAB |
1mg |
EUR 2826 |
|
Recombinant Drosophila melanogaster Thioredoxin-2 (Trx-2) |
CSB-EP892681DLU |
Cusabio |
4820 mg |
Ask for price |
Recombinant Drosophila melanogaster Partner of bursicon(pburs) |
AP73149 |
SAB |
1mg |
EUR 3389 |
|
Recombinant Drosophila melanogaster Partner of bursicon(pburs) |
AP71619 |
SAB |
1mg |
EUR 2826 |
|
Recombinant Drosophila melanogaster Partner of bursicon (pburs) |
CSB-EP893290DLU |
Cusabio |
4821 mg |
Ask for price |
Recombinant Drosophila melanogaster Partner of bursicon (pburs) |
CSB-YP893290DLU |
Cusabio |
6744 mg |
Ask for price |
Recombinant Drosophila melanogaster Protein nanos (nos), partial |
CSB-EP340723DLU1 |
Cusabio |
11681 mg |
Ask for price |
OPCA01354-100UG - Recombinant Drosophila melanogaster Bursicon |
OPCA01354-100UG |
Aviva Systems Biology |
100ug |
EUR 668 |
|
OPCA01354-20UG - Recombinant Drosophila melanogaster Bursicon |
OPCA01354-20UG |
Aviva Systems Biology |
20ug |
EUR 449 |
|
OPCA01354-500UG - Recombinant Drosophila melanogaster Bursicon |
OPCA01354-500UG |
Aviva Systems Biology |
500ug |
EUR 1534 |
|
Recombinant (E.Coli, GST tag) Drosophila melanogaster GAGA-POZ |
RP-881 |
Alpha Diagnostics |
10 ug |
EUR 270 |
Recombinant Drosophila melanogaster 40S ribosomal protein S3(RpS3) |
AP77875 |
SAB |
1mg |
EUR 2826 |
|
Recombinant Drosophila melanogaster 40S ribosomal protein S3 (RpS3) |
CSB-EP020443DLU |
Cusabio |
2099 mg |
Ask for price |
Recombinant Drosophila melanogaster 60S ribosomal protein L10 (RpL10) |
RPC28210-100ug |
Biomatik Corporation |
100ug |
EUR 765.5 |
Recombinant Drosophila melanogaster 60S ribosomal protein L10 (RpL10) |
RPC28210-1mg |
Biomatik Corporation |
1mg |
EUR 2959.2 |
Recombinant Drosophila melanogaster 60S ribosomal protein L10 (RpL10) |
RPC28210-20ug |
Biomatik Corporation |
20ug |
EUR 448.1 |
Recombinant Drosophila melanogaster Brain tumor protein (brat), partial |
CSB-EP839760DLU |
Cusabio |
11677 mg |
Ask for price |
Recombinant Drosophila melanogaster 60S ribosomal protein L10 (RpL10) |
CSB-EP020106DLU |
Cusabio |
2088 mg |
Ask for price |
Recombinant Drosophila melanogaster Clathrin heavy chain (Chc), partial |
CSB-EP333472DLU |
Cusabio |
11688 mg |
Ask for price |
Recombinant Drosophila melanogaster Maternal protein pumilio (pum), partial |
CSB-EP326575DLU |
Cusabio |
11678 mg |
Ask for price |
Recombinant Drosophila melanogaster Probable insulin-like peptide 7 (Ilp7) |
CSB-BP895238DLU |
Cusabio |
7612 mg |
Ask for price |
Recombinant Drosophila melanogaster Spectrin beta chain (beta-Spec), partial |
CSB-EP251598DLU |
Cusabio |
11684 mg |
Ask for price |
Recombinant Drosophila melanogaster Stress-activated protein kinase JNK(bsk) |
AP74472 |
SAB |
1mg |
EUR 2826 |
|
Recombinant Drosophila melanogaster Stress-activated protein kinase JNK (bsk) |
CSB-BP310094DLU |
Cusabio |
138 mg |
Ask for price |
Recombinant Drosophila melanogaster Stress-activated protein kinase JNK (bsk) |
CSB-EP310094DLU |
Cusabio |
2689 mg |
Ask for price |
Recombinant Drosophila melanogaster General odorant-binding protein lush(lush) |
AP77163 |
SAB |
1mg |
EUR 2826 |
|
Recombinant Drosophila melanogaster General odorant-binding protein lush (lush) |
CSB-EP517298DLU |
Cusabio |
3585 mg |
Ask for price |
Recombinant Drosophila melanogaster Cyclin-dependent kinase 12 (Cdk12), partial |
CSB-EP894718DLU |
Cusabio |
10841 mg |
Ask for price |
Recombinant Drosophila melanogaster Maternal effect protein staufen (stau), partial |
CSB-EP329523DLU |
Cusabio |
11679 mg |
Ask for price |
Drosophila melanogaster Protein numb homolog (NUMB) control (non-phospho) peptide |
AB-23106-CP |
Alpha Diagnostics |
100ug |
EUR 196.8 |
Drosophila melanogaster Protein numb homolog (NUMB) control (NUMB- phosphor) peptide |
AB-23106-P |
Alpha Diagnostics |
100ug |
EUR 196.8 |
Recombinant Drosophila melanogaster Ubiquitin-conjugating enzyme E2-17KDA(UbcD6) |
AP73726 |
SAB |
each |
Ask for price |
|
Recombinant Drosophila melanogaster Ubiquitin-conjugating enzyme E2-17KDA(UbcD6) |
AP71042 |
SAB |
1mg |
EUR 2826 |
|
Recombinant Drosophila melanogaster 28S ribosomal protein S10, mitochondrial (mRpS10) |
CSB-EP894684DLU |
Cusabio |
11073 mg |
Ask for price |
Recombinant Drosophila melanogaster Ubiquitin-conjugating enzyme E2-17KDA (UbcD6) |
CSB-EP328517DLU |
Cusabio |
2953 mg |
Ask for price |
Recombinant Drosophila melanogaster Ubiquitin-conjugating enzyme E2-17KDA (UbcD6) |
CSB-YP328517DLU |
Cusabio |
6231 mg |
Ask for price |
OPCA00305-100UG - Recombinant Drosophila melanogaster Partner of bursicon(pburs) Protein |
OPCA00305-100UG |
Aviva Systems Biology |
100ug |
EUR 586 |
|
OPCA00305-1MG - Recombinant Drosophila melanogaster Partner of bursicon(pburs) Protein |
OPCA00305-1MG |
Aviva Systems Biology |
1mg |
EUR 1977 |
|
OPCA00305-20UG - Recombinant Drosophila melanogaster Partner of bursicon(pburs) Protein |
OPCA00305-20UG |
Aviva Systems Biology |
20ug |
EUR 400 |
|
OPCA01353-100UG - Recombinant Drosophila melanogaster Partner of bursicon(pburs) Protein |
OPCA01353-100UG |
Aviva Systems Biology |
100ug |
EUR 668 |
|
OPCA01353-1MG - Recombinant Drosophila melanogaster Partner of bursicon(pburs) Protein |
OPCA01353-1MG |
Aviva Systems Biology |
1mg |
EUR 2368 |
|
OPCA01353-20UG - Recombinant Drosophila melanogaster Partner of bursicon(pburs) Protein |
OPCA01353-20UG |
Aviva Systems Biology |
20ug |
EUR 449 |
|
Recombinant Drosophila melanogaster Stress-activated protein kinase JNK(bsk),partial |
AP74727 |
SAB |
each |
Ask for price |
|
Recombinant Drosophila melanogaster Peptidoglycan-recognition protein SC2 (PGRP-SC2) |
CSB-EP892684DLU |
Cusabio |
8976 mg |
Ask for price |
Recombinant Drosophila melanogaster Glyceraldehyde-3-phosphate dehydrogenase 1 (Gapdh1) |
CSB-EP362145DLU |
Cusabio |
3395 mg |
Ask for price |
Drosophila melanogaster Bursicon (burs) |
1-CSB-YP894207DLU |
Cusabio |
-
EUR 814.80
-
EUR 402.00
-
EUR 2606.40
-
EUR 1261.20
-
EUR 1730.40
-
EUR 522.00
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Drosophila melanogaster Bursicon(burs) expressed in Yeast |
Drosophila melanogaster Bursicon (burs) |
1-CSB-EP894207DLU |
Cusabio |
-
EUR 733.20
-
EUR 370.80
-
EUR 2192.40
-
EUR 1126.80
-
EUR 1461.60
-
EUR 476.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Drosophila melanogaster Bursicon(burs) expressed in E.coli |
Recombinant Drosophila melanogaster cAMP-dependent protein kinase catalytic subunit(Pka-C1) |
AP74305 |
SAB |
1mg |
EUR 2826 |
|
Recombinant Drosophila melanogaster cAMP-dependent protein kinase catalytic subunit (Pka-C1) |
CSB-EP318954DLU |
Cusabio |
2769 mg |
Ask for price |
Recombinant Drosophila melanogaster DNA-directed RNA polymerase II subunit RPB1(RpII215),partial |
AP74371 |
SAB |
each |
Ask for price |
|
Recombinant Drosophila melanogaster DNA-directed RNA polymerase II subunit RPB1 (RpII215), partial |
CSB-YP018327DLU |
Cusabio |
5920 mg |
Ask for price |
Recombinant Drosophila melanogaster Sterile alpha and TIR motif-containing protein 1 (Ect4), partial |
CSB-EP764228DLU1 |
Cusabio |
9036 mg |
Ask for price |
Drosophila melanogaster GAGA-POZ Protein |
20-abx260436 |
Abbexa |
-
EUR 276.00
-
EUR 2798.40
-
EUR 393.60
|
|
|
Recombinant Drosophila melanogaster Protein-L-isoaspartate (D-aspartate) O-methyltransferase (Pcmt) |
RPC28423-100ug |
Biomatik Corporation |
100ug |
EUR 801.9 |
Recombinant Drosophila melanogaster Protein-L-isoaspartate (D-aspartate) O-methyltransferase (Pcmt) |
RPC28423-1mg |
Biomatik Corporation |
1mg |
EUR 2885.2 |
Recombinant Drosophila melanogaster Protein-L-isoaspartate (D-aspartate) O-methyltransferase (Pcmt) |
RPC28423-20ug |
Biomatik Corporation |
20ug |
EUR 448.1 |
Recombinant Drosophila melanogaster Protein-L-isoaspartate (D-aspartate) O-methyltransferase(Pcmt) |
CSB-EP635664DLU |
Cusabio |
7088 mg |
Ask for price |
Drosophila melanogaster Protein bottleneck (bnk) |
1-CSB-EP328169DLU |
Cusabio |
-
EUR 733.20
-
EUR 370.80
-
EUR 2192.40
-
EUR 1126.80
-
EUR 1461.60
-
EUR 476.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Drosophila melanogaster Protein bottleneck(bnk) expressed in E.coli |
Drosophila melanogaster Thioredoxin-2 (Trx-2) |
1-CSB-EP892681DLU |
Cusabio |
-
EUR 733.20
-
EUR 370.80
-
EUR 2192.40
-
EUR 1126.80
-
EUR 1461.60
-
EUR 476.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Drosophila melanogaster Thioredoxin-2(Trx-2) expressed in E.coli |
Drosophila melanogaster Partner of bursicon (pburs) |
1-CSB-YP893290DLU |
Cusabio |
-
EUR 814.80
-
EUR 402.00
-
EUR 2606.40
-
EUR 1261.20
-
EUR 1730.40
-
EUR 522.00
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Drosophila melanogaster Partner of bursicon(pburs) expressed in Yeast |
Drosophila melanogaster Partner of bursicon (pburs) |
1-CSB-EP893290DLU |
Cusabio |
-
EUR 733.20
-
EUR 370.80
-
EUR 2192.40
-
EUR 1126.80
-
EUR 1461.60
-
EUR 476.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Drosophila melanogaster Partner of bursicon(pburs) expressed in E.coli |
Recombinant Drosophila melanogaster NADH-ubiquinone oxidoreductase 75KDA subunit, mitochondria(ND75),partial |
AP73837 |
SAB |
1mg |
EUR 2826 |
|
Recombinant Drosophila melanogaster NADH-ubiquinone oxidoreductase 75KDA subunit, mitochondria (ND75),partial |
CSB-EP821986DLU |
Cusabio |
4238 mg |
Ask for price |
Drosophila melanogaster 40S ribosomal protein S3 (RpS3) |
1-CSB-EP020443DLU |
Cusabio |
-
EUR 606.00
-
EUR 318.00
-
EUR 2192.40
-
EUR 919.20
-
EUR 1461.60
-
EUR 402.00
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Drosophila melanogaster 40S ribosomal protein S3(RpS3) expressed in E.coli |
Drosophila melanogaster 60S ribosomal protein L10 (RpL10) |
1-CSB-EP020106DLU |
Cusabio |
-
EUR 733.20
-
EUR 370.80
-
EUR 2192.40
-
EUR 1126.80
-
EUR 1461.60
-
EUR 476.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Drosophila melanogaster 60S ribosomal protein L10(RpL10) expressed in E.coli |
Drosophila Melanogaster GAPDH Rabbit Polyclonal Antibody |
E12-1006 |
EnoGene |
100μg/100μl |
EUR 255 |
Description: Available in various conjugation types. |
Drosophila Melanogaster GAPDH Rabbit Polyclonal Antibody |
RA20337-100ul |
Reed Biotech |
100 ul |
EUR 298 |
Drosophila Melanogaster GAPDH Rabbit Polyclonal Antibody |
RA20337-50ul |
Reed Biotech |
50 ul |
EUR 198 |
Drosophila Melanogaster GAPDH Mouse Monoclonal Antibody (7B7) |
E12-1076 |
EnoGene |
100μg/100μl |
EUR 255 |
Description: Available in various conjugation types. |
Drosophila Melanogaster GAPDH Mouse Monoclonal Antibody(7B7) |
RA10323-100ul |
Reed Biotech |
100 ul |
EUR 298 |
Drosophila Melanogaster GAPDH Mouse Monoclonal Antibody(7B7) |
RA10323-50ul |
Reed Biotech |
50 ul |
EUR 198 |
Drosophila Melanogaster β-actin Rabbit Polyclonal Antibody |
E12-1005 |
EnoGene |
100μg/100μl |
EUR 255 |
Description: Available in various conjugation types. |
Drosophila Melanogaster β-actin Rabbit Polyclonal Antibody |
RA20336-100ul |
Reed Biotech |
100 ul |
EUR 298 |
Drosophila Melanogaster β-actin Rabbit Polyclonal Antibody |
RA20336-50ul |
Reed Biotech |
50 ul |
EUR 198 |
Anti-Loki / Chk2 (Drosophila melanogaster aa115-128) antibody |
STJ72761 |
St John's Laboratory |
100 µg |
EUR 312 |
Drosophila melanogaster Stress-activated protein kinase JNK (bsk) |
1-CSB-BP310094DLU |
Cusabio |
-
EUR 913.20
-
EUR 367.20
-
EUR 2341.20
-
EUR 1231.20
-
EUR 1706.40
-
EUR 517.20
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Drosophila melanogaster Stress-activated protein kinase JNK(bsk) expressed in Baculovirus |
Drosophila melanogaster Stress-activated protein kinase JNK (bsk) |
1-CSB-EP310094DLU |
Cusabio |
-
EUR 733.20
-
EUR 370.80
-
EUR 2192.40
-
EUR 1126.80
-
EUR 1461.60
-
EUR 476.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Drosophila melanogaster Stress-activated protein kinase JNK(bsk) expressed in E.coli |
Drosophila melanogaster General odorant-binding protein lush (lush) |
1-CSB-EP517298DLU |
Cusabio |
-
EUR 733.20
-
EUR 370.80
-
EUR 2192.40
-
EUR 1126.80
-
EUR 1461.60
-
EUR 476.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Drosophila melanogaster General odorant-binding protein lush(lush) expressed in E.coli |
Drosophila Melanogaster β-actin Mouse Monoclonal Antibody (Mix-mA) |
E12-1020 |
EnoGene |
100μg/100μl |
EUR 255 |
Description: Available in various conjugation types. |
Recombinant Drosophila melanogaster Sterile alpha and TIR motif-containing protein 1 (Ect4) (A386L,H392R,T433V,T434A,L595S,A596D,H599Q), partial |
CSB-EP764228DLU1(M) |
Cusabio |
9026 mg |
Ask for price |
Drosophila melanogaster Ubiquitin-conjugating enzyme E2-17KDA (UbcD6) |
1-CSB-EP328517DLU |
Cusabio |
-
EUR 733.20
-
EUR 370.80
-
EUR 2192.40
-
EUR 1126.80
-
EUR 1461.60
-
EUR 476.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Drosophila melanogaster Ubiquitin-conjugating enzyme E2-17KDA(UbcD6) expressed in E.coli |
Drosophila melanogaster Ubiquitin-conjugating enzyme E2-17KDA (UbcD6) |
1-CSB-YP328517DLU |
Cusabio |
-
EUR 814.80
-
EUR 402.00
-
EUR 2606.40
-
EUR 1261.20
-
EUR 1730.40
-
EUR 522.00
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Drosophila melanogaster Ubiquitin-conjugating enzyme E2-17KDA(UbcD6) expressed in Yeast |
Drosophila melanogaster Glyceraldehyde-3-phosphate dehydrogenase 1 (Gapdh1) |
1-CSB-EP362145DLU |
Cusabio |
-
EUR 733.20
-
EUR 370.80
-
EUR 2192.40
-
EUR 1126.80
-
EUR 1461.60
-
EUR 476.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Drosophila melanogaster Glyceraldehyde-3-phosphate dehydrogenase 1(Gapdh1) expressed in E.coli |
Drosophila melanogaster DNA-directed RNA polymerase II subunit RPB1 (RpII215) |
1-CSB-YP018327DLU |
Cusabio |
-
EUR 814.80
-
EUR 402.00
-
EUR 2606.40
-
EUR 1261.20
-
EUR 1730.40
-
EUR 522.00
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Drosophila melanogaster DNA-directed RNA polymerase II subunit RPB1(RpII215),partial expressed in Yeast |
Drosophila melanogaster cAMP-dependent protein kinase catalytic subunit (Pka-C1) |
1-CSB-EP318954DLU |
Cusabio |
-
EUR 733.20
-
EUR 370.80
-
EUR 2192.40
-
EUR 1126.80
-
EUR 1461.60
-
EUR 476.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Drosophila melanogaster cAMP-dependent protein kinase catalytic subunit(Pka-C1) expressed in E.coli |
Drosophila melanogaster NADH-ubiquinone oxidoreductase 75KDA subunit, mitochondria (ND75) |
1-CSB-EP821986DLU |
Cusabio |
-
EUR 733.20
-
EUR 370.80
-
EUR 2192.40
-
EUR 1126.80
-
EUR 1461.60
-
EUR 476.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Drosophila melanogaster NADH-ubiquinone oxidoreductase 75KDA subunit, mitochondria(ND75),partial expressed in E.coli |
Drosophila melanogaster phosphotyrosyl phosphatase activator (PTPA) control (non-phosphor) peptide |
AB-23094-CP |
Alpha Diagnostics |
100ug |
EUR 562.8 |
Drosophila melanogaster phosphotyrosyl phosphatase activator (PTPA) control (PTPA- phosphor) peptide |
AB-23094-P |
Alpha Diagnostics |
100ug |
EUR 196.8 |
Recombinant Serum Response Factor (SRF) |
4-RPA515Hu01 |
Cloud-Clone |
-
EUR 582.34
-
EUR 279.60
-
EUR 1853.76
-
EUR 697.92
-
EUR 1275.84
-
EUR 465.60
-
EUR 4454.40
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Human Serum Response Factor expressed in: E.coli |
Recombinant Serum Response Factor (SRF) |
RPA515Hu01 |
Cloud-Clone |
10ug |
EUR 172 |
Recombinant human Serum response factor |
P2250 |
FN Test |
100ug |
Ask for price |
|
Description: Recombinant protein for human Serum response factor |
Recombinant Mouse Serum response factor(Srf) |
AP73609 |
SAB |
1mg |
EUR 2826 |
|
Recombinant Human Serum response factor(SRF) |
AP77814 |
SAB |
each |
Ask for price |
|
Recombinant Mouse Serum response factor (Srf) |
CSB-EP881354MO |
Cusabio |
4702 mg |
Ask for price |
Recombinant Human Serum response factor (SRF) |
CSB-YP022659HU |
Cusabio |
6019 mg |
Ask for price |
(untagged)-Human cDNA FLJ38163 fis, clone DFNES2003192, weakly similar to Drosophila melanogaster mRNA for fucosyltransferase (FucTB gene) |
SC312202 |
Origene Technologies GmbH |
10 µg |
Ask for price |
(untagged)-Human cDNA FLJ30648 fis, clone CTONG2006449, moderately similar to Drosophila melanogaster 26S proteasome regulatory complex subunit p |
SC312261 |
Origene Technologies GmbH |
10 µg |
Ask for price |
Recombinant Serum Response Factor Binding Protein 1 (SRFBP1) |
RPU57528-100ug |
Biomatik Corporation |
100ug |
EUR 470.4 |
Recombinant Serum Response Factor Binding Protein 1 (SRFBP1) |
RPU57528-1mg |
Biomatik Corporation |
1mg |
EUR 2184 |
Recombinant Serum Response Factor Binding Protein 1 (SRFBP1) |
RPU57528-50ug |
Biomatik Corporation |
50ug |
EUR 385 |
Recombinant Serum Response Factor Binding Protein 1 (SRFBP1) |
RPU58310-100ug |
Biomatik Corporation |
100ug |
EUR 537.6 |
Recombinant Serum Response Factor Binding Protein 1 (SRFBP1) |
RPU58310-1mg |
Biomatik Corporation |
1mg |
EUR 2496 |
Recombinant Serum Response Factor Binding Protein 1 (SRFBP1) |
RPU58310-50ug |
Biomatik Corporation |
50ug |
EUR 418 |
Recombinant Serum Response Factor Binding Protein 1 (SRFBP1) |
RPG306Hu01 |
Cloud-Clone |
10ug |
EUR 160 |
Recombinant Serum Response Factor Binding Protein 1 (SRFBP1) |
RPG306Mu01 |
Cloud-Clone |
10ug |
EUR 140 |
Rabbit Anti-Drosophila melanogaster Protein numb homolog (NUMB) (NUMB- phosphor) IgG (aff pure) |
AB-23106-A |
Alpha Diagnostics |
100ug |
EUR 578.4 |
Recombinant Mouse Serum response factor Protein, His-SUMO, E.coli-10ug |
QP8177-ec-10ug |
EnQuireBio |
10ug |
EUR 391.2 |
Recombinant Mouse Serum response factor Protein, His-SUMO, E.coli-1mg |
QP8177-ec-1mg |
EnQuireBio |
1mg |
EUR 2763.6 |
Recombinant Mouse Serum response factor Protein, His-SUMO, E.coli-50ug |
QP8177-ec-50ug |
EnQuireBio |
50ug |
EUR 522 |
Recombinant Mouse Serum response factor Protein, His-SUMO, E.coli-100ug |
QP8177-ec-100ug |
EnQuireBio |
100ug |
EUR 848.4 |
Recombinant Mouse Serum response factor Protein, His-SUMO, E.coli-200ug |
QP8177-ec-200ug |
EnQuireBio |
200ug |
EUR 1338 |
Recombinant Mouse Serum response factor Protein, His-SUMO, E.coli-500ug |
QP8177-ec-500ug |
EnQuireBio |
500ug |
EUR 1816.8 |
Serum response factor |
AP87612 |
SAB |
1mg |
EUR 2640 |
|
Serum response factor |
AP88441 |
SAB |
1mg |
EUR 2640 |
|
Serum response factor |
AP88461 |
SAB |
1mg |
EUR 2640 |
|
Human Serum response factor (SRF) |
1-CSB-YP022659HU |
Cusabio |
-
EUR 703.20
-
EUR 358.80
-
EUR 2606.40
-
EUR 1080.00
-
EUR 1730.40
-
EUR 458.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Human Serum response factor(SRF) expressed in Yeast |
Mouse Serum response factor (Srf) |
1-CSB-EP881354MO |
Cusabio |
-
EUR 733.20
-
EUR 370.80
-
EUR 2192.40
-
EUR 1126.80
-
EUR 1461.60
-
EUR 476.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Mouse Serum response factor(Srf) expressed in E.coli |
Serum Response Factor (SRF) Antibody |
20-abx318707 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Serum Response Factor (SRF) Antibody |
abx238222-100ug |
Abbexa |
100 ug |
EUR 610.8 |
|
Serum Response Factor (SRF) Antibody |
20-abx213101 |
Abbexa |
|
|
|
Serum Response Factor (SRF) Antibody |
20-abx141089 |
Abbexa |
-
EUR 427.20
-
EUR 644.40
-
EUR 260.40
|
|
|
Serum Response Factor (SRF) Antibody |
20-abx325825 |
Abbexa |
|
|
|
Serum Response Factor (SRF) Antibody |
20-abx325916 |
Abbexa |
|
|
|
Serum Response Factor (SRF) Antibody |
20-abx115482 |
Abbexa |
|
|
|
Serum Response Factor (SRF) Antibody |
20-abx128713 |
Abbexa |
-
EUR 477.60
-
EUR 159.60
-
EUR 1312.80
-
EUR 644.40
-
EUR 376.80
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Serum Response Factor (SRF) Antibody |
20-abx329082 |
Abbexa |
|
|
|
Serum Response Factor (SRF) Antibody |
abx431612-200ul |
Abbexa |
200 ul |
EUR 460.8 |
|
Serum Response Factor (SRF) Antibody |
20-abx008686 |
Abbexa |
-
EUR 360.00
-
EUR 526.80
-
EUR 226.80
|
|
|
Serum Response Factor (SRF) Antibody |
20-abx000712 |
Abbexa |
|
|
|
Serum Response Factor (SRF) Antibody |
abx012108-100ug |
Abbexa |
100 ug |
EUR 526.8 |
|
Serum Response Factor (SRF) Antibody |
abx012110-100ug |
Abbexa |
100 ug |
EUR 526.8 |
|
Serum Response Factor Antibody (Srf) |
F52804-0.08ML |
NSJ Bioreagents |
0.08 ml |
EUR 140.25 |
Description: SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS) (By similarity). Required for cardiac differentiation and maturation. |
Serum Response Factor Antibody / SRF |
RQ6341 |
NSJ Bioreagents |
100 ug |
EUR 356.15 |
Description: Serum response factor, also known as SRF, is a transcription factor protein. This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene. |
SRF Antibody / Serum Response Factor |
RQ6521 |
NSJ Bioreagents |
100ug |
EUR 356.15 |
Description: Serum response factor, also known as SRF, is a transcription factor protein. This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene. |
Serum Response Factor (SRF) ELISA Kit |
abx595562-96tests |
Abbexa |
96 tests |
EUR 764.4 |
|
Subsequently, we famous the involvement of the mTOR/S6k/4E-BP candidates in mitigating poly(Q) mediated neurotoxicity. Because of the conserved mobile functioning of the insulin cascade throughout species, and availability of a number of progress selling molecules, our leads to Drosophila poly(Q) fashions point out in the direction of a risk of designing novel therapeutic methods to limit the pathogenesis of devastating human poly(Q) issues.
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