Natural Zeitgebers Under Temperate Conditions Cannot Compensate for the Loss of a Functional Circadian Clock in Timing of a Vital Behavior in Drosophila

Natural Zeitgebers Under Temperate Conditions Cannot Compensate for the Loss of a Functional Circadian Clock in Timing of a Vital Behavior in Drosophila

Natural Zeitgebers Under Temperate Conditions Cannot Compensate for the Loss of a Functional Circadian Clock in Timing of a Vital Behavior in Drosophila

The adaptive significance of adjusting behavioral actions to the best time of the day appears apparent. Laboratory research implicated an essential position of circadian clocks in behavioral timing and rhythmicity. But, latest research on clock-mutant animals questioned this significance below extra naturalistic settings, as numerous clock mutants confirmed almost regular diel exercise rhythms below seminatural zeitgeber circumstances.
We right here report proof that correct timing of eclosion, a significant habits of the fruit fly Drosophila melanogaster, requires a purposeful molecular clock below quasi-natural circumstances. In distinction to wild-type flies, interval01 mutants with a faulty molecular clock confirmed impaired rhythmicity and gating in a temperate setting even within the presence of a full complement of abiotic zeitgebers. Though interval01 mutants nonetheless eclosed throughout a sure time window in the course of the day, this time window was a lot broader and loosely outlined, and rhythmicity was decrease or misplaced as categorized by numerous statistical measures. Furthermore, peak eclosion time turned extra inclined to variable day-to-day modifications of sunshine.
In distinction, flies with impaired peptidergic interclock signaling (Pdf01 and han5304 PDF receptor mutants) eclosed largely rhythmically with regular gate sizes, much like wild-type controls. Our outcomes recommend that the presence of pure zeitgebers isn’t adequate, and a purposeful molecular clock is required to induce steady temporal eclosion patterns in flies below temperate circumstances with appreciable day-to-day variation in gentle depth and temperature. Temperate zeitgebers are, nonetheless, adequate to functionally rescue a lack of PDF-mediated clock-internal and -output signaling.

Nanda-Hamner Curves Present Large Latitudinal Variation however No Circadian Elements in Drosophila Montana Photoperiodism

Insect species with a large distribution provide an important alternative to hint latitudinal variation within the photoperiodic regulation of traits essential in copy and stress tolerances. We measured this variation within the photoperiodic time-measuring system underlying reproductive diapause in Drosophila montana, utilizing a Nanda-Hamner (NH) protocol. Not one of the research strains confirmed diel rhythmicity in feminine diapause proportions below a continuing day size (12 h) and ranging night time lengths in photoperiods starting from 16 to 84 h at 16°C. Within the northernmost strains (above 55°N), almost all females entered diapause below all photoperiods and about half of them even in steady darkness, whereas the females of the southern strains confirmed excessive diapause proportions solely within the circadian 24 h photoperiod.
Important correlation between the strains’ imply diapause proportions in ≥ 24 h photoperiods and important day size (CDL; half of the females enter diapause) suggests at the least partial causal connection between the traits. Apparently, females of the northern strains entered diapause even in ≤ 24 h photoperiods, the place the night time size was shorter than their important night time size (24 h – CDL), however the place the females skilled a better variety of Gentle:Darkish cycles than in 24 h photoperiods.
NH experiments, carried out on the management and choice strains in our earlier choice experiment, and accomplished right here, gave comparable outcomes and confirmed that choice for shorter, southern-type CDL decreases feminine diapausing fee in non-circadian photoperiods. Total, our research exhibits that D. montana females measure night time size quantitatively, that the photoperiodic counter could play a distinguished however barely totally different position in further quick and further lengthy photoperiods and that northern strains present excessive stability towards perturbations within the photoperiod size and within the presence of LD cycles. These options are finest defined by the quantitative variations of the damped exterior coincidence mannequin.
Natural Zeitgebers Under Temperate Conditions Cannot Compensate for the Loss of a Functional Circadian Clock in Timing of a Vital Behavior in Drosophila

Interaction between intercourse willpower cascade and main signaling pathways throughout Drosophila eye improvement: Views for future analysis

Understanding molecular mechanisms of sexually dimorphic organ progress is a elementary downside of developmental biology. Current quantitative research confirmed that the Drosophila compound eye is a handy mannequin to review the willpower of the ultimate organ measurement. In Drosophila, females have bigger eyes than males and that is evident even after correction for the bigger physique measurement. Furthermore, feminine eyes embody extra ommatidia (photosensitive items) than male eyes and this distinction is specified on the third larval instar within the eye primordia referred to as eye imaginal discs. This will likely end in totally different visible capabilities between the 2 sexes and have behavioral penalties.
Regardless of rising proof on the genetic bases of eye measurement variation between totally different Drosophila species and strains, mechanisms accountable for within-species sexual dimorphism nonetheless stay elusive. Right here, we focus on a presumptive crosstalk between the intercourse willpower cascade and main signaling pathways throughout dimorphic eye improvement. Male- and female-specific isoforms of Doublesex (Dsx) protein are identified to regulate sex-specific differentiation within the somatic tissues. Nonetheless, no information on Dsx perform throughout eye disc progress and patterning are presently accessible.
Remarkably, Intercourse deadly (Sxl), the intercourse willpower change protein, was proven to straight have an effect on Hedgehog (Hh) and Notch (N) signaling within the Drosophila wing disc. The similarity of signaling pathways concerned within the wing and eye disc progress means that Sxl is perhaps built-in into regulation of eye improvement. Dsx position within the eye disc requires additional investigation. We focus on presently accessible information on sex-biased gene expression within the Drosophila eye and spotlight views for future research.

DNA polymerase theta suppresses mitotic crossing over

Polymerase theta-mediated finish becoming a member of (TMEJ) is a chromosome break restore pathway that is ready to rescue the lethality related to the lack of proteins concerned in early steps in homologous recombination (e.g., BRCA1/2). That is because of the capacity of polymerase theta (Pol θ) to make use of resected, 3′ single stranded DNA tails to restore chromosome breaks. These resected DNA tails are additionally the beginning substrate for homologous recombination. Nonetheless, it stays unknown if TMEJ can compensate for the lack of proteins concerned in additional downstream steps throughout homologous recombination. Right here we present that the Holliday junction resolvases SLX4 and GEN1 are required for viability within the absence of Pol θ in Drosophila melanogaster, and lack of all three proteins ends in excessive ranges of apoptosis.
Flies poor in Pol θ and SLX4 are extraordinarily delicate to DNA damaging brokers, and mammalian cells require both Pol θ or SLX4 to outlive. Our outcomes recommend that TMEJ and Holliday junction formation/decision share a standard DNA substrate, seemingly a homologous recombination intermediate, that when left unrepaired results in cell demise. One main consequence of Holliday junction decision by SLX4 and GEN1 is cancer-causing lack of heterozygosity as a consequence of mitotic crossing over. We measured mitotic crossovers in flies after a Cas9-induced chromosome break, and noticed that this mutagenic type of restore is elevated within the absence of Pol θ.

Monoclonal COPB Antibody (monoclonal) (M08), Clone: 3E11

APR15551G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human COPB (monoclonal) (M08). The antibodies are raised in mouse and are from clone 3E11. This antibody is applicable in E

Monoclonal FBL Antibody (monoclonal) (M09), Clone: 3E11

APR15927G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human FBL (monoclonal) (M09). The antibodies are raised in mouse and are from clone 3E11. This antibody is applicable in E

Monoclonal ATP7B Antibody (monoclonal) (M01), Clone: 3E11

APG02168G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human ATP7B (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3E11. This antibody is applicable in WB, E

Monoclonal HIP1R Antibody (monoclonal) (M01), Clone: 3E11

APR12375G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human HIP1R (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3E11. This antibody is applicable in WB, E

Monoclonal COPl Antibody (monoclonal) (M01), Clone: 3E11

AMM03405G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human COPl (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3E11. This antibody is applicable in WB, E

Monoclonal HERPUD1 Antibody (monoclonal) (M01), Clone: 3E11

AMM03617G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human HERPUD1 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3E11. This antibody is applicable in WB, E

Monoclonal ID3 Antibody (monoclonal) (M02), Clone: 3E11

AMM03649G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human ID3 (monoclonal) (M02). The antibodies are raised in Mouse and are from clone 3E11. This antibody is applicable in WB and IF, E

Monoclonal LY6H Antibody (monoclonal) (M01), Clone: 3E11

AMM03754G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human LY6H (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3E11. This antibody is applicable in WB and IHC

Monoclonal MAP2K5 Antibody (monoclonal) (M11), Clone: 3E11

AMM03762G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human MAP2K5 (monoclonal) (M11). The antibodies are raised in mouse and are from clone 3E11. This antibody is applicable in WB and IF, E

Monoclonal SMARCB1 Antibody (monoclonal) (M01), Clone: 3E11

AMM04112G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human SMARCB1 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3E11. This antibody is applicable in WB and IHC

Monoclonal PDLIM5 Antibody (monoclonal) (M01), Clone: 3E11-F6

APR12791G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human PDLIM5 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3E11-F6. This antibody is applicable in WB and IF, E

Anti Mummichog Vitellogenin Monoclonal Antibody (Clone No. 3E11)

KH005
EUR 544
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anti-HDAC3 (3E11)

LF-MA10133 100 ug
EUR 363
Description: Mouse monoclonal to HDAC3

Anti-Twist (3E11)

YF-MA10977 100 ug
EUR 363
Description: Mouse monoclonal to Twist

Anti-cvHSP (3E11)

YF-MA11450 100 ug
EUR 363
Description: Mouse monoclonal to cvHSP

Anti-AKT1 (3E11)

YF-MA11876 100 ug
EUR 363
Description: Mouse monoclonal to AKT1

Anti-OSGIN2 (3E11)

YF-MA12209 100 ug
EUR 363
Description: Mouse monoclonal to OSGIN2

Anti-FMRP (3E11)

YF-MA13101 100 ug
EUR 363
Description: Mouse monoclonal to FMRP

Anti-MCM3 (3E11)

YF-MA14152 100 ug
EUR 363
Description: Mouse monoclonal to MCM3

Anti-NHLH2 (3E11)

YF-MA14458 100 ug
EUR 363
Description: Mouse monoclonal to NHLH2

Anti-POMC (3E11)

YF-MA14807 100 ug
EUR 363
Description: Mouse monoclonal to POMC

Anti-RPL23A (3E11)

YF-MA15244 100 ug
EUR 363
Description: Mouse monoclonal to RPL23A

Anti-Psoriasin (3E11)

YF-MA15314 50 ug
EUR 363
Description: Mouse monoclonal to Psoriasin

Anti-Psoriasin (3E11)

YF-MA15315 200 ul
EUR 363
Description: Mouse monoclonal to Psoriasin

Anti-Osteopontin (3E11)

YF-MA15581 100 ug
EUR 363
Description: Mouse monoclonal to Osteopontin

Anti-TCF2 (3E11)

YF-MA15765 100 ug
EUR 363
Description: Mouse monoclonal to TCF2

Anti-KLF10 (3E11)

YF-MA15849 100 ug
EUR 363
Description: Mouse monoclonal to KLF10

Anti-ZNF187 (3E11)

YF-MA16192 100 ug
EUR 363
Description: Mouse monoclonal to ZNF187

Anti-CER1 (3E11)

YF-MA16795 100 ug
EUR 363
Description: Mouse monoclonal to CER1

Anti-TIP30 (3E11)

YF-MA17378 100 ug
EUR 363
Description: Mouse monoclonal to TIP30

Anti-CCRK (3E11)

YF-MA17926 100 ug
EUR 363
Description: Mouse monoclonal to CCRK

Anti-BTBD1 (3E11)

YF-MA18595 100 ug
EUR 363
Description: Mouse monoclonal to BTBD1

Anti-ALS2CR2 (3E11)

YF-MA18781 100 ug
EUR 363
Description: Mouse monoclonal to ALS2CR2

Anti-SPG (3E11)

YF-MA18829 50 ug
EUR 363
Description: Mouse monoclonal to SPG

Anti-MRPS36 (3E11)

YF-MA19657 100 ug
EUR 363
Description: Mouse monoclonal to MRPS36

Anti-MPO (3E11)

YF-MA20367 100 ug
EUR 363
Description: Mouse monoclonal to MPO

Anti-ARFGEF1 (3E11)

YF-MA20498 100 ug
EUR 363
Description: Mouse monoclonal to ARFGEF1

Monoclonal Ku (p70/p80)Mouse Monoclonal Antibody [Clone KU729], Clone: KU729

AMM00210G 0.5ml
EUR 484
Description: A Monoclonal antibody against Human Ku (p70/p80)Mouse Monoclonal [Clone KU729]. The antibodies are raised in Mouse and are from clone KU729. This antibody is applicable in IF, FC

Monoclonal mouse Splunc2 Antibody, Clone: 1F12

APR07136G 0.1ml
EUR 528
Description: A Monoclonal antibody against Human mouse Splunc2. The antibodies are raised in Mouse and are from clone 1F12. This antibody is applicable in WB and IHC, FC, ICC, E

Monoclonal mouse Lplunc1 Antibody, Clone: 4H2

APR08492G 0.1ml
EUR 528
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Monoclonal mouse Lplunc1 Antibody, Clone: 1F11E3

APR08493G 0.1ml
EUR 528
Description: A Monoclonal antibody against Human mouse Lplunc1. The antibodies are raised in Mouse and are from clone 1F11E3. This antibody is applicable in WB, E

Monoclonal Mouse Bmi1 Antibody, Clone: 353CT22.4.4

AMM02383G 0.1ml
EUR 484
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Monoclonal NGFR Antibody (Clone # 8G3G10), Clone: Clone # 8G3G10

AMM06686G 0.1ml
EUR 484
Description: A Monoclonal antibody against Human NGFR (Clone # 8G3G10). The antibodies are raised in Mouse and are from clone Clone # 8G3G10. This antibody is applicable in WB and IF, FC

Monoclonal S100A8 Antibody (Clone IMG48M7C7), Clone: Clone IMG48M7C7

AMM00015G 0.1mg
EUR 528
Description: A Monoclonal antibody against Human S100A8 (Clone IMG48M7C7). The antibodies are raised in Mouse and are from clone Clone IMG48M7C7. This antibody is applicable in WB and IHC

Monoclonal PDGFR Antibody (Clone # 275CT1), Clone: Clone # 275CT1

AMM00020G 0.05ml
EUR 484
Description: A Monoclonal antibody against Human PDGFR (Clone # 275CT1). The antibodies are raised in Mouse and are from clone Clone # 275CT1. This antibody is applicable in WB

Monoclonal CD11c FITC Monoclonal Antibody (Clone 3.9), Clone: 3.9

APR15331G 50 tests
EUR 484
Description: A Monoclonal antibody against Human CD11c FITC Monoclonal (Clone 3.9). The antibodies are raised in Mouse and are from clone 3.9. This antibody is applicable in FC

Monoclonal CD28 FITC Monoclonal Antibody (Clone CD28.2), Clone: CD28.2

AMM00025G 0.05mg
EUR 396
Description: A Monoclonal antibody against Human CD28 FITC Monoclonal (Clone CD28.2). The antibodies are raised in Mouse and are from clone CD28.2. This antibody is applicable in FC

Monoclonal CST3 Antibody (monoclonal), Clone: 1H4

AMM03425G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human CST3 (monoclonal). The antibodies are raised in Mouse and are from clone 1H4. This antibody is applicable in WB

Monoclonal TNFSF18 Antibody (monoclonal), Clone: 2E11

AMM04221G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human TNFSF18 (monoclonal). The antibodies are raised in mouse and are from clone 2E11. This antibody is applicable in WB, E

Monoclonal FTL Antibody (monoclonal), Clone: 4G7

AMM04622G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human FTL (monoclonal). The antibodies are raised in Mouse and are from clone 4G7. This antibody is applicable in WB, E

anti-Progesteron Receptor (3E11)

LF-MA10230 100 ug
EUR 363
Description: Mouse monoclonal to Progesteron Receptor

Anti-ORC2 (3E11-1G5)

YF-MA10652 100 ug
EUR 363
Description: Mouse monoclonal to ORC2

Anti-PDLIM5 (3E11-F6)

YF-MA11302 100 ug
EUR 363
Description: Mouse monoclonal to PDLIM5

Anti-IkB beta (3E11)

YF-MA14442 100 ug
EUR 363
Description: Mouse monoclonal to IkB beta

Monoclonal HEXA Antibody (clone AT20F1), Clone: AT20F1

APC00059G 0.05ml
EUR 484
Description: A Monoclonal antibody against Human HEXA (clone AT20F1). The antibodies are raised in Mouse and are from clone AT20F1. This antibody is applicable in WB and IHC-P, E

Monoclonal MAG Antibody (clone 3C7), Clone: 3C7

APC00061G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human MAG (clone 3C7). The antibodies are raised in Mouse and are from clone 3C7. This antibody is applicable in WB and IHC-P, E

Monoclonal MAP1B Antibody (clone 3G5), Clone: 3G5

APC00063G 0.1ml
EUR 484
Description: A Monoclonal antibody against Human MAP1B (clone 3G5). The antibodies are raised in Mouse and are from clone 3G5. This antibody is applicable in IHC-P, IF

Monoclonal DUX4 Antibody (clone P2B1), Clone: P2B1

APC00110G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human DUX4 (clone P2B1). The antibodies are raised in Mouse and are from clone P2B1. This antibody is applicable in WB and IHC-P, IF

Monoclonal CPS1 Antibody (clone 8H8), Clone: 8H8

APG02746G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human CPS1 (clone 8H8). The antibodies are raised in Mouse and are from clone 8H8. This antibody is applicable in WB and IHC-P, E

Monoclonal CTH Antibody (clone 2D6), Clone: 2D6

APG02819G 0.05ml
EUR 484
Description: A Monoclonal antibody against Human CTH (clone 2D6). The antibodies are raised in Mouse and are from clone 2D6. This antibody is applicable in WB and IHC-P

Monoclonal CYP1A1 Antibody (clone 6G5), Clone: 6G5

APG02871G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human CYP1A1 (clone 6G5). The antibodies are raised in Mouse and are from clone 6G5. This antibody is applicable in WB and IHC-P, E

Monoclonal CAMK4 Antibody (clone 1A3), Clone: 1A3

APG03190G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human CAMK4 (clone 1A3). The antibodies are raised in Mouse and are from clone 1A3. This antibody is applicable in WB and IHC-P, IF, E

Monoclonal CAMKK1 Antibody (clone 1F6), Clone: 1F6

APG03194G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human CAMKK1 (clone 1F6). The antibodies are raised in Mouse and are from clone 1F6. This antibody is applicable in WB and IHC-P, E

Monoclonal EMX2 Antibody (clone 4F7), Clone: 4F7

APG03285G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human EMX2 (clone 4F7). The antibodies are raised in Mouse and are from clone 4F7. This antibody is applicable in IHC-P, E

Monoclonal RAPGEF6 Antibody (clone 2C5), Clone: 2C5

AMM07531G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human RAPGEF6 (clone 2C5). The antibodies are raised in Mouse and are from clone 2C5. This antibody is applicable in WB and IHC-P, IF, E

Monoclonal SOCS1 Antibody (clone 4H1), Clone: 4H1

AMM07943G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human SOCS1 (clone 4H1). The antibodies are raised in Mouse and are from clone 4H1. This antibody is applicable in WB and IHC-P

Monoclonal STK16 Antibody (clone M2), Clone: M2

AMM08020G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human STK16 (clone M2). The antibodies are raised in Mouse and are from clone M2. This antibody is applicable in WB and IHC-P, E, RNAi

Monoclonal STK33 Antibody (clone 3F10), Clone: 3F10

AMM08027G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human STK33 (clone 3F10). The antibodies are raised in Mouse and are from clone 3F10. This antibody is applicable in WB and IHC-P, IF, E

Monoclonal TNNI2 Antibody (clone 11E6), Clone: 11E6

AMM08268G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human TNNI2 (clone 11E6). The antibodies are raised in Mouse and are from clone 11E6. This antibody is applicable in WB and IHC-P, E

Monoclonal TNNI2 Antibody (clone 2F12G2), Clone: 2F12G2

AMM08269G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human TNNI2 (clone 2F12G2). The antibodies are raised in Mouse and are from clone 2F12G2. This antibody is applicable in WB and IHC-P, IF, ICC, E, Flo

Monoclonal TTC1 Antibody (clone 4E3), Clone: 4E3

AMM08362G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human TTC1 (clone 4E3). The antibodies are raised in Mouse and are from clone 4E3. This antibody is applicable in WB and IHC-P, E

Monoclonal TUBB2B Antibody (clone AT5B3), Clone: AT5B3

AMM08382G 0.05ml
EUR 484
Description: A Monoclonal antibody against Human TUBB2B (clone AT5B3). The antibodies are raised in Mouse and are from clone AT5B3. This antibody is applicable in IHC-P

Monoclonal VASP Antibody (clone 4D6), Clone: 4D6

AMM08458G 0.05ml
EUR 484
Description: A Monoclonal antibody against Human VASP (clone 4D6). The antibodies are raised in Mouse and are from clone 4D6. This antibody is applicable in WB and IHC-P, IF, Flo

Monoclonal CD34 Antibody (clone EP88), Clone: EP88

AMR03190G 0.05ml
EUR 484
Description: A Monoclonal antibody against Human CD34 (clone EP88). The antibodies are raised in Rabbit and are from clone EP88. This antibody is applicable in IHC-P, IHC-Fr

Monoclonal PLCG1 Antibody (clone 2B1), Clone: 2B1

AMR09352G 0.05ml
EUR 484
Description: A Monoclonal antibody against Human PLCG1 (clone 2B1). The antibodies are raised in Mouse and are from clone 2B1. This antibody is applicable in WB and IHC-P, IP

Monoclonal PNMT Antibody (clone AT1C11), Clone: AT1C11

AMR09408G 0.05ml
EUR 484
Description: A Monoclonal antibody against Human PNMT (clone AT1C11). The antibodies are raised in Mouse and are from clone AT1C11. This antibody is applicable in WB and IHC-P, E

Monoclonal PNPO Antibody (clone AT2C7), Clone: AT2C7

AMR09416G 0.05ml
EUR 484
Description: A Monoclonal antibody against Human PNPO (clone AT2C7). The antibodies are raised in Mouse and are from clone AT2C7. This antibody is applicable in WB and IHC-P, E

Monoclonal PON3 Antibody (clone 5G11), Clone: 5G11

AMR09422G 0.05ml
EUR 484
Description: A Monoclonal antibody against Human PON3 (clone 5G11). The antibodies are raised in Mouse and are from clone 5G11. This antibody is applicable in WB and IHC-P

Monoclonal PTGES3 Antibody (clone JJ6), Clone: JJ6

AMR09608G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human PTGES3 (clone JJ6). The antibodies are raised in Mouse and are from clone JJ6. This antibody is applicable in WB and IHC-P, E, IP

Monoclonal PTP1B Antibody (Clone 107AT531), Clone: 107AT531

AMR09648G 0.1mg
EUR 528
Description: A Monoclonal antibody against Human PTP1B (Clone 107AT531). The antibodies are raised in Mouse and are from clone 107AT531. This antibody is applicable in WB, E

Monoclonal PYGM Antibody (clone 2C4), Clone: 2C4

AMR09675G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human PYGM (clone 2C4). The antibodies are raised in Mouse and are from clone 2C4. This antibody is applicable in WB and IHC-P, E

Monoclonal REG1A Antibody (clone 1A4), Clone: 1A4

AMR09710G 0.05ml
EUR 484
Description: A Monoclonal antibody against Human REG1A (clone 1A4). The antibodies are raised in Mouse and are from clone 1A4. This antibody is applicable in IHC-P, IF, E

Monoclonal SDSL Antibody (clone M2), Clone: M2

AMR09854G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human SDSL (clone M2). The antibodies are raised in Mouse and are from clone M2. This antibody is applicable in WB and IHC-P, E

Monoclonal CD34 Antibody (clone MEC14.7), Clone: MEC14.7

AMRa00010G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human CD34 (clone MEC14.7). The antibodies are raised in Rat and are from clone MEC14.7. This antibody is applicable in IHC-P, IP, Flo

Monoclonal CD44 Antibody (clone IM7), Clone: IM7

AMRa00013G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human CD44 (clone IM7). The antibodies are raised in Rat and are from clone IM7. This antibody is applicable in WB and IHC-P, ICC, IP, IHC-Fr, Flo

Monoclonal EBI3 Antibody (clone DNT27), Clone: DNT27

AMRa00014G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human EBI3 (clone DNT27). The antibodies are raised in Rat and are from clone DNT27. This antibody is applicable in WB and IHC-P

Monoclonal SLC13A5 Antibody (clone 2G4), Clone: 2G4

APR09978G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human SLC13A5 (clone 2G4). The antibodies are raised in Mouse and are from clone 2G4. This antibody is applicable in WB and IHC-P, E

Monoclonal SLC22A1 Antibody (clone 2C5), Clone: 2C5

APR10013G 0.05ml
EUR 484
Description: A Monoclonal antibody against Human SLC22A1 (clone 2C5). The antibodies are raised in Mouse and are from clone 2C5. This antibody is applicable in WB and IHC-P, E, Flo

Monoclonal SMAD3 Antibody (clone 2C12), Clone: 2C12

APR10161G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human SMAD3 (clone 2C12). The antibodies are raised in Mouse and are from clone 2C12. This antibody is applicable in WB and IHC-P, E

Monoclonal SMAD3 Antibody (clone AF9F7), Clone: AF9F7

APR10162G 0.05ml
EUR 484
Description: A Monoclonal antibody against Human SMAD3 (clone AF9F7). The antibodies are raised in Mouse and are from clone AF9F7. This antibody is applicable in WB and IHC-P, E, IP

Monoclonal SOCS3 Antibody (clone SO1), Clone: SO1

APR10171G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human SOCS3 (clone SO1). The antibodies are raised in Mouse and are from clone SO1. This antibody is applicable in WB and IHC-P, E

Monoclonal SOD3 Antibody (clone 1H12), Clone: 1H12

APR10200G 0.05ml
EUR 484
Description: A Monoclonal antibody against Human SOD3 (clone 1H12). The antibodies are raised in Mouse and are from clone 1H12. This antibody is applicable in WB and IHC-P, E, IP

Monoclonal STAT1 Antibody (clone AT1FA), Clone: AT1FA

APR10265G 0.05ml
EUR 484
Description: A Monoclonal antibody against Human STAT1 (clone AT1FA). The antibodies are raised in Mouse and are from clone AT1FA. This antibody is applicable in WB and IHC-P, E

Monoclonal STAT1 Antibody (clone SM1), Clone: SM1

APR10266G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human STAT1 (clone SM1). The antibodies are raised in Mouse and are from clone SM1. This antibody is applicable in WB and IHC-P, IP

Monoclonal STAT5A Antibody (clone 9F7), Clone: 9F7

APR10279G 0.05ml
EUR 484
Description: A Monoclonal antibody against Human STAT5A (clone 9F7). The antibodies are raised in Mouse and are from clone 9F7. This antibody is applicable in WB and IHC-P, IF, Flo

Monoclonal STAT5B Antibody (clone 2D1), Clone: 2D1

APR10281G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human STAT5B (clone 2D1). The antibodies are raised in Mouse and are from clone 2D1. This antibody is applicable in WB and IHC-P, IF, E
This demonstrates that TMEJ can perform upstream of the Vacation junction resolvases to guard cells from lack of heterozygosity. Our work argues that Pol θ can thus compensate for the lack of the Holliday junction resolvases by utilizing homologous recombination intermediates, suppressing mitotic crossing over and preserving the genomic stability of cells.