Natural Zeitgebers Under Temperate Conditions Cannot Compensate for the Loss of a Functional Circadian Clock in Timing of a Vital Behavior in Drosophila

Natural Zeitgebers Under Temperate Conditions Cannot Compensate for the Loss of a Functional Circadian Clock in Timing of a Vital Behavior in Drosophila

Natural Zeitgebers Under Temperate Conditions Cannot Compensate for the Loss of a Functional Circadian Clock in Timing of a Vital Behavior in Drosophila

The adaptive significance of adjusting behavioral actions to the best time of the day appears apparent. Laboratory research implicated an essential position of circadian clocks in behavioral timing and rhythmicity. But, latest research on clock-mutant animals questioned this significance below extra naturalistic settings, as numerous clock mutants confirmed almost regular diel exercise rhythms below seminatural zeitgeber circumstances.
We right here report proof that correct timing of eclosion, a significant habits of the fruit fly Drosophila melanogaster, requires a purposeful molecular clock below quasi-natural circumstances. In distinction to wild-type flies, interval01 mutants with a faulty molecular clock confirmed impaired rhythmicity and gating in a temperate setting even within the presence of a full complement of abiotic zeitgebers. Though interval01 mutants nonetheless eclosed throughout a sure time window in the course of the day, this time window was a lot broader and loosely outlined, and rhythmicity was decrease or misplaced as categorized by numerous statistical measures. Furthermore, peak eclosion time turned extra inclined to variable day-to-day modifications of sunshine.
In distinction, flies with impaired peptidergic interclock signaling (Pdf01 and han5304 PDF receptor mutants) eclosed largely rhythmically with regular gate sizes, much like wild-type controls. Our outcomes recommend that the presence of pure zeitgebers isn’t adequate, and a purposeful molecular clock is required to induce steady temporal eclosion patterns in flies below temperate circumstances with appreciable day-to-day variation in gentle depth and temperature. Temperate zeitgebers are, nonetheless, adequate to functionally rescue a lack of PDF-mediated clock-internal and -output signaling.

Nanda-Hamner Curves Present Large Latitudinal Variation however No Circadian Elements in Drosophila Montana Photoperiodism

Insect species with a large distribution provide an important alternative to hint latitudinal variation within the photoperiodic regulation of traits essential in copy and stress tolerances. We measured this variation within the photoperiodic time-measuring system underlying reproductive diapause in Drosophila montana, utilizing a Nanda-Hamner (NH) protocol. Not one of the research strains confirmed diel rhythmicity in feminine diapause proportions below a continuing day size (12 h) and ranging night time lengths in photoperiods starting from 16 to 84 h at 16°C. Within the northernmost strains (above 55°N), almost all females entered diapause below all photoperiods and about half of them even in steady darkness, whereas the females of the southern strains confirmed excessive diapause proportions solely within the circadian 24 h photoperiod.
Important correlation between the strains’ imply diapause proportions in ≥ 24 h photoperiods and important day size (CDL; half of the females enter diapause) suggests at the least partial causal connection between the traits. Apparently, females of the northern strains entered diapause even in ≤ 24 h photoperiods, the place the night time size was shorter than their important night time size (24 h – CDL), however the place the females skilled a better variety of Gentle:Darkish cycles than in 24 h photoperiods.
NH experiments, carried out on the management and choice strains in our earlier choice experiment, and accomplished right here, gave comparable outcomes and confirmed that choice for shorter, southern-type CDL decreases feminine diapausing fee in non-circadian photoperiods. Total, our research exhibits that D. montana females measure night time size quantitatively, that the photoperiodic counter could play a distinguished however barely totally different position in further quick and further lengthy photoperiods and that northern strains present excessive stability towards perturbations within the photoperiod size and within the presence of LD cycles. These options are finest defined by the quantitative variations of the damped exterior coincidence mannequin.
Natural Zeitgebers Under Temperate Conditions Cannot Compensate for the Loss of a Functional Circadian Clock in Timing of a Vital Behavior in Drosophila

Interaction between intercourse willpower cascade and main signaling pathways throughout Drosophila eye improvement: Views for future analysis

Understanding molecular mechanisms of sexually dimorphic organ progress is a elementary downside of developmental biology. Current quantitative research confirmed that the Drosophila compound eye is a handy mannequin to review the willpower of the ultimate organ measurement. In Drosophila, females have bigger eyes than males and that is evident even after correction for the bigger physique measurement. Furthermore, feminine eyes embody extra ommatidia (photosensitive items) than male eyes and this distinction is specified on the third larval instar within the eye primordia referred to as eye imaginal discs. This will likely end in totally different visible capabilities between the 2 sexes and have behavioral penalties.
Regardless of rising proof on the genetic bases of eye measurement variation between totally different Drosophila species and strains, mechanisms accountable for within-species sexual dimorphism nonetheless stay elusive. Right here, we focus on a presumptive crosstalk between the intercourse willpower cascade and main signaling pathways throughout dimorphic eye improvement. Male- and female-specific isoforms of Doublesex (Dsx) protein are identified to regulate sex-specific differentiation within the somatic tissues. Nonetheless, no information on Dsx perform throughout eye disc progress and patterning are presently accessible.
Remarkably, Intercourse deadly (Sxl), the intercourse willpower change protein, was proven to straight have an effect on Hedgehog (Hh) and Notch (N) signaling within the Drosophila wing disc. The similarity of signaling pathways concerned within the wing and eye disc progress means that Sxl is perhaps built-in into regulation of eye improvement. Dsx position within the eye disc requires additional investigation. We focus on presently accessible information on sex-biased gene expression within the Drosophila eye and spotlight views for future research.

DNA polymerase theta suppresses mitotic crossing over

Polymerase theta-mediated finish becoming a member of (TMEJ) is a chromosome break restore pathway that is ready to rescue the lethality related to the lack of proteins concerned in early steps in homologous recombination (e.g., BRCA1/2). That is because of the capacity of polymerase theta (Pol θ) to make use of resected, 3′ single stranded DNA tails to restore chromosome breaks. These resected DNA tails are additionally the beginning substrate for homologous recombination. Nonetheless, it stays unknown if TMEJ can compensate for the lack of proteins concerned in additional downstream steps throughout homologous recombination. Right here we present that the Holliday junction resolvases SLX4 and GEN1 are required for viability within the absence of Pol θ in Drosophila melanogaster, and lack of all three proteins ends in excessive ranges of apoptosis.
Flies poor in Pol θ and SLX4 are extraordinarily delicate to DNA damaging brokers, and mammalian cells require both Pol θ or SLX4 to outlive. Our outcomes recommend that TMEJ and Holliday junction formation/decision share a standard DNA substrate, seemingly a homologous recombination intermediate, that when left unrepaired results in cell demise. One main consequence of Holliday junction decision by SLX4 and GEN1 is cancer-causing lack of heterozygosity as a consequence of mitotic crossing over. We measured mitotic crossovers in flies after a Cas9-induced chromosome break, and noticed that this mutagenic type of restore is elevated within the absence of Pol θ.

Monoclonal HERPUD1 Antibody (monoclonal) (M01), Clone: 3E11

AMM03617G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human HERPUD1 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3E11. This antibody is applicable in WB, E

Monoclonal ID3 Antibody (monoclonal) (M02), Clone: 3E11

AMM03649G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human ID3 (monoclonal) (M02). The antibodies are raised in Mouse and are from clone 3E11. This antibody is applicable in WB and IF, E

Monoclonal LY6H Antibody (monoclonal) (M01), Clone: 3E11

AMM03754G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human LY6H (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3E11. This antibody is applicable in WB and IHC

Monoclonal MAP2K5 Antibody (monoclonal) (M11), Clone: 3E11

AMM03762G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human MAP2K5 (monoclonal) (M11). The antibodies are raised in mouse and are from clone 3E11. This antibody is applicable in WB and IF, E

Monoclonal SMARCB1 Antibody (monoclonal) (M01), Clone: 3E11

AMM04112G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human SMARCB1 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3E11. This antibody is applicable in WB and IHC

Monoclonal ATP7B Antibody (monoclonal) (M01), Clone: 3E11

APG02168G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human ATP7B (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3E11. This antibody is applicable in WB, E

Monoclonal PDLIM5 Antibody (monoclonal) (M01), Clone: 3E11-F6

APR12791G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human PDLIM5 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3E11-F6. This antibody is applicable in WB and IF, E

Anti Mummichog Vitellogenin Monoclonal Antibody (Clone No. 3E11)

KH005
EUR 544
Description: The Anti Mummichog Vitellogenin Monoclonal Antibody (Clone No. 3E11) is available in Europe and for worldwide shipping via Gentaur.

anti-HDAC3 (3E11)

LF-MA10133 100 ug
EUR 363
Description: Mouse monoclonal to HDAC3

Anti-Twist (3E11)

YF-MA10977 100 ug
EUR 363
Description: Mouse monoclonal to Twist

Anti-cvHSP (3E11)

YF-MA11450 100 ug
EUR 363
Description: Mouse monoclonal to cvHSP

Anti-AKT1 (3E11)

YF-MA11876 100 ug
EUR 363
Description: Mouse monoclonal to AKT1

Anti-OSGIN2 (3E11)

YF-MA12209 100 ug
EUR 363
Description: Mouse monoclonal to OSGIN2

Anti-FMRP (3E11)

YF-MA13101 100 ug
EUR 363
Description: Mouse monoclonal to FMRP

Anti-MCM3 (3E11)

YF-MA14152 100 ug
EUR 363
Description: Mouse monoclonal to MCM3

Anti-NHLH2 (3E11)

YF-MA14458 100 ug
EUR 363
Description: Mouse monoclonal to NHLH2

Anti-POMC (3E11)

YF-MA14807 100 ug
EUR 363
Description: Mouse monoclonal to POMC

Anti-RPL23A (3E11)

YF-MA15244 100 ug
EUR 363
Description: Mouse monoclonal to RPL23A

Anti-Psoriasin (3E11)

YF-MA15314 50 ug
EUR 363
Description: Mouse monoclonal to Psoriasin

Anti-Psoriasin (3E11)

YF-MA15315 200 ul
EUR 363
Description: Mouse monoclonal to Psoriasin

Anti-Osteopontin (3E11)

YF-MA15581 100 ug
EUR 363
Description: Mouse monoclonal to Osteopontin

Anti-TCF2 (3E11)

YF-MA15765 100 ug
EUR 363
Description: Mouse monoclonal to TCF2

Anti-KLF10 (3E11)

YF-MA15849 100 ug
EUR 363
Description: Mouse monoclonal to KLF10

Anti-ZNF187 (3E11)

YF-MA16192 100 ug
EUR 363
Description: Mouse monoclonal to ZNF187

Anti-CER1 (3E11)

YF-MA16795 100 ug
EUR 363
Description: Mouse monoclonal to CER1

Anti-TIP30 (3E11)

YF-MA17378 100 ug
EUR 363
Description: Mouse monoclonal to TIP30

Anti-CCRK (3E11)

YF-MA17926 100 ug
EUR 363
Description: Mouse monoclonal to CCRK

Anti-BTBD1 (3E11)

YF-MA18595 100 ug
EUR 363
Description: Mouse monoclonal to BTBD1

Anti-ALS2CR2 (3E11)

YF-MA18781 100 ug
EUR 363
Description: Mouse monoclonal to ALS2CR2

Anti-SPG (3E11)

YF-MA18829 50 ug
EUR 363
Description: Mouse monoclonal to SPG

Anti-MRPS36 (3E11)

YF-MA19657 100 ug
EUR 363
Description: Mouse monoclonal to MRPS36

Anti-MPO (3E11)

YF-MA20367 100 ug
EUR 363
Description: Mouse monoclonal to MPO

Anti-ARFGEF1 (3E11)

YF-MA20498 100 ug
EUR 363
Description: Mouse monoclonal to ARFGEF1

Monoclonal Ku (p70/p80)Mouse Monoclonal Antibody [Clone KU729], Clone: KU729

AMM00210G 0.5ml
EUR 484
Description: A Monoclonal antibody against Human Ku (p70/p80)Mouse Monoclonal [Clone KU729]. The antibodies are raised in Mouse and are from clone KU729. This antibody is applicable in IF, FC

Monoclonal Mouse Bmi1 Antibody, Clone: 353CT22.4.4

AMM02383G 0.1ml
EUR 484
Description: A Monoclonal antibody against Human Mouse Bmi1. The antibodies are raised in Mouse and are from clone 353CT22.4.4. This antibody is applicable in WB, E

Monoclonal mouse Splunc2 Antibody, Clone: 1F12

APR07136G 0.1ml
EUR 528
Description: A Monoclonal antibody against Human mouse Splunc2. The antibodies are raised in Mouse and are from clone 1F12. This antibody is applicable in WB and IHC, FC, ICC, E

Monoclonal mouse Lplunc1 Antibody, Clone: 4H2

APR08492G 0.1ml
EUR 528
Description: A Monoclonal antibody against Human mouse Lplunc1. The antibodies are raised in Mouse and are from clone 4H2. This antibody is applicable in WB and IHC, FC, ICC, E

Monoclonal mouse Lplunc1 Antibody, Clone: 1F11E3

APR08493G 0.1ml
EUR 528
Description: A Monoclonal antibody against Human mouse Lplunc1. The antibodies are raised in Mouse and are from clone 1F11E3. This antibody is applicable in WB, E

Monoclonal NGFR Antibody (Clone # 8G3G10), Clone: Clone # 8G3G10

AMM06686G 0.1ml
EUR 484
Description: A Monoclonal antibody against Human NGFR (Clone # 8G3G10). The antibodies are raised in Mouse and are from clone Clone # 8G3G10. This antibody is applicable in WB and IF, FC

Monoclonal S100A8 Antibody (Clone IMG48M7C7), Clone: Clone IMG48M7C7

AMM00015G 0.1mg
EUR 528
Description: A Monoclonal antibody against Human S100A8 (Clone IMG48M7C7). The antibodies are raised in Mouse and are from clone Clone IMG48M7C7. This antibody is applicable in WB and IHC

Monoclonal PDGFR Antibody (Clone # 275CT1), Clone: Clone # 275CT1

AMM00020G 0.05ml
EUR 484
Description: A Monoclonal antibody against Human PDGFR (Clone # 275CT1). The antibodies are raised in Mouse and are from clone Clone # 275CT1. This antibody is applicable in WB

Monoclonal CD11c FITC Monoclonal Antibody (Clone 3.9), Clone: 3.9

APR15331G 50 tests
EUR 484
Description: A Monoclonal antibody against Human CD11c FITC Monoclonal (Clone 3.9). The antibodies are raised in Mouse and are from clone 3.9. This antibody is applicable in FC

Monoclonal CD28 FITC Monoclonal Antibody (Clone CD28.2), Clone: CD28.2

AMM00025G 0.05mg
EUR 396
Description: A Monoclonal antibody against Human CD28 FITC Monoclonal (Clone CD28.2). The antibodies are raised in Mouse and are from clone CD28.2. This antibody is applicable in FC

Monoclonal CST3 Antibody (monoclonal), Clone: 1H4

AMM03425G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human CST3 (monoclonal). The antibodies are raised in Mouse and are from clone 1H4. This antibody is applicable in WB

Monoclonal TNFSF18 Antibody (monoclonal), Clone: 2E11

AMM04221G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human TNFSF18 (monoclonal). The antibodies are raised in mouse and are from clone 2E11. This antibody is applicable in WB, E

Monoclonal FTL Antibody (monoclonal), Clone: 4G7

AMM04622G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human FTL (monoclonal). The antibodies are raised in Mouse and are from clone 4G7. This antibody is applicable in WB, E

anti-Progesteron Receptor (3E11)

LF-MA10230 100 ug
EUR 363
Description: Mouse monoclonal to Progesteron Receptor

Anti-ORC2 (3E11-1G5)

YF-MA10652 100 ug
EUR 363
Description: Mouse monoclonal to ORC2

Anti-PDLIM5 (3E11-F6)

YF-MA11302 100 ug
EUR 363
Description: Mouse monoclonal to PDLIM5

Anti-IkB beta (3E11)

YF-MA14442 100 ug
EUR 363
Description: Mouse monoclonal to IkB beta

Monoclonal VLDLR Antibody (clone 1H10), Clone: 1H10

APR10743G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human VLDLR (clone 1H10). The antibodies are raised in Mouse and are from clone 1H10. This antibody is applicable in WB and IHC-P, E

Monoclonal VNN1 Antibody (clone 4E11), Clone: 4E11

APR10746G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human VNN1 (clone 4E11). The antibodies are raised in Mouse and are from clone 4E11. This antibody is applicable in IHC-P, E

Monoclonal BPIFB1 Antibody (clone 2A5), Clone: 2A5

APR11011G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human BPIFB1 (clone 2A5). The antibodies are raised in Mouse and are from clone 2A5. This antibody is applicable in WB and IHC-P, IF, ICC, E, Flo

Monoclonal GMEB1 Antibody (clone 2A8), Clone: 2A8

APR11097G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human GMEB1 (clone 2A8). The antibodies are raised in Mouse and are from clone 2A8. This antibody is applicable in WB and IHC-P, IF, E

Monoclonal STAT3 Antibody (clone 7G3H4), Clone: 7G3H4

APR11201G 0.05ml
EUR 484
Description: A Monoclonal antibody against Human STAT3 (clone 7G3H4). The antibodies are raised in Mouse and are from clone 7G3H4. This antibody is applicable in WB and IHC-P, E

Monoclonal TLR4 Antibody (clone 3B6), Clone: 3B6

APR11219G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human TLR4 (clone 3B6). The antibodies are raised in Mouse and are from clone 3B6. This antibody is applicable in WB and IHC-P, E

Monoclonal CRIM1 Antibody (clone 6E4), Clone: 6E4

APR11670G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human CRIM1 (clone 6E4). The antibodies are raised in Mouse and are from clone 6E4. This antibody is applicable in WB and IHC-P, E

Monoclonal DLX2 Antibody (clone 2E12), Clone: 2E12

APR11769G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human DLX2 (clone 2E12). The antibodies are raised in Mouse and are from clone 2E12. This antibody is applicable in WB and IHC-P, E

Monoclonal DLX2 Antibody (clone 4B9), Clone: 4B9

APR11770G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human DLX2 (clone 4B9). The antibodies are raised in Mouse and are from clone 4B9. This antibody is applicable in WB and IHC-P, E

Monoclonal HAS2 Antibody (clone 4E7), Clone: 4E7

APR12329G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human HAS2 (clone 4E7). The antibodies are raised in Mouse and are from clone 4E7. This antibody is applicable in WB and IHC-P, IF, ICC, E

Monoclonal HIP1 Antibody (clone 1F12), Clone: 1F12

APR12372G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human HIP1 (clone 1F12). The antibodies are raised in Mouse and are from clone 1F12. This antibody is applicable in WB and IHC-P, E, IP

Monoclonal HMX2 Antibody (clone 1B10), Clone: 1B10

APR12392G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human HMX2 (clone 1B10). The antibodies are raised in Mouse and are from clone 1B10. This antibody is applicable in WB and IHC-P, E

Monoclonal HMX2 Antibody (clone 1D7), Clone: 1D7

APR12393G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human HMX2 (clone 1D7). The antibodies are raised in Mouse and are from clone 1D7. This antibody is applicable in WB and IHC-P, E

Monoclonal MAP2 Antibody (clone 5F9), Clone: 5F9

APR12495G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human MAP2 (clone 5F9). The antibodies are raised in Mouse and are from clone 5F9. This antibody is applicable in WB and IHC-P

Monoclonal PAX2 Antibody (clone 3C7), Clone: 3C7

APR12728G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human PAX2 (clone 3C7). The antibodies are raised in Mouse and are from clone 3C7. This antibody is applicable in WB and IHC-P, E

Monoclonal PAX5 Antibody (clone 1H9), Clone: 1H9

APR12733G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human PAX5 (clone 1H9). The antibodies are raised in Rat and are from clone 1H9. This antibody is applicable in WB and IHC-P, IHC-Fr

Monoclonal PAX5 Antibody (clone 7D3), Clone: 7D3

APR12734G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human PAX5 (clone 7D3). The antibodies are raised in Mouse and are from clone 7D3. This antibody is applicable in WB and IHC-P, E

Monoclonal PAX5 Antibody (clone 7D3), Clone: 7D3

APR12735G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human PAX5 (clone 7D3). The antibodies are raised in Mouse and are from clone 7D3. This antibody is applicable in WB and IHC-P, E

Monoclonal PAX5 Antibody (clone 8F9), Clone: 8F9

APR12736G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human PAX5 (clone 8F9). The antibodies are raised in Mouse and are from clone 8F9. This antibody is applicable in WB and IHC-P, E

Monoclonal PPP2R2B Antibody (clone 1F3), Clone: 1F3

APR12943G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human PPP2R2B (clone 1F3). The antibodies are raised in Mouse and are from clone 1F3. This antibody is applicable in WB and IHC-P, E, IP

Monoclonal SOX10 Antibody (clone 1E6), Clone: 1E6

APR13452G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human SOX10 (clone 1E6). The antibodies are raised in Mouse and are from clone 1E6. This antibody is applicable in WB and IHC-P, E

Monoclonal SOX9 Antibody (clone 3C10), Clone: 3C10

APR13496G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human SOX9 (clone 3C10). The antibodies are raised in Mouse and are from clone 3C10. This antibody is applicable in WB and IHC-P, IF, E

Monoclonal SOX9 Antibody (clone 3F11), Clone: 3F11

APR13497G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human SOX9 (clone 3F11). The antibodies are raised in Mouse and are from clone 3F11. This antibody is applicable in WB and IHC-P, IF, E

Monoclonal YY1 Antibody (clone 2C4), Clone: 2C4

APR14010G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human YY1 (clone 2C4). The antibodies are raised in Mouse and are from clone 2C4. This antibody is applicable in WB and IHC-P, IF, E

Monoclonal YY1 Antibody (clone 4A5), Clone: 4A5

APR14011G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human YY1 (clone 4A5). The antibodies are raised in Mouse and are from clone 4A5. This antibody is applicable in WB and IHC-P, IF, E

Monoclonal YY1 Antibody (clone 4D2), Clone: 4D2

APR14012G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human YY1 (clone 4D2). The antibodies are raised in Mouse and are from clone 4D2. This antibody is applicable in WB and IHC-P, IF, E

Monoclonal ZIC4 Antibody (clone 2B9), Clone: 2B9

APR14042G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human ZIC4 (clone 2B9). The antibodies are raised in Mouse and are from clone 2B9. This antibody is applicable in WB and IHC-P, E

Monoclonal Zyxin Antibody (clone 2D1), Clone: 2D1

APR14060G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human Zyxin (clone 2D1). The antibodies are raised in Mouse and are from clone 2D1. This antibody is applicable in WB and IHC-P, E

Monoclonal C4d Antibody [Clone C4D205], Clone: C4D205

AMM00082G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human C4d [Clone C4D205]. The antibodies are raised in Mouse and are from clone C4D205. This antibody is applicable in IF

Monoclonal Vimentin Antibody [Clone LN6], Clone: LN6

AMM00156G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human Vimentin [Clone LN6]. The antibodies are raised in Mouse and are from clone LN6. This antibody is applicable in WB, IHC and IF

Monoclonal C4d Antibody [Clone TDM16], Clone: TDM16

AMM00188G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human C4d [Clone TDM16]. The antibodies are raised in Mouse and are from clone TDM16. This antibody is applicable in IF

Monoclonal CD33 Antibody [Clone WM53], Clone: WM53

AMM00203G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human CD33 [Clone WM53]. The antibodies are raised in Mouse and are from clone WM53. This antibody is applicable in FC

Monoclonal CD33 Antibody [Clone WM53], Clone: WM53

AMM00204G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human CD33 [Clone WM53]. The antibodies are raised in Mouse and are from clone WM53. This antibody is applicable in FC

Monoclonal CD59 Antibody (clone 1F5), Clone: 1F5

AMM01702G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human CD59 (clone 1F5). The antibodies are raised in Mouse and are from clone 1F5. This antibody is applicable in IHC-P, Flo

Monoclonal TIMP2 Antibody (clone F27P3A4), Clone: F27P3A4

AMM01705G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human TIMP2 (clone F27P3A4). The antibodies are raised in Mouse and are from clone F27P3A4. This antibody is applicable in WB and IHC-P, E

Monoclonal NFKB1 Antibody (clone 4D1), Clone: 4D1

AMM01706G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human NFKB1 (clone 4D1). The antibodies are raised in Mouse and are from clone 4D1. This antibody is applicable in WB and IHC-P, IF

Monoclonal CD74 Antibody (clone LN2), Clone: LN2

AMM01728G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human CD74 (clone LN2). The antibodies are raised in Mouse and are from clone LN2. This antibody is applicable in IHC-P, IP, Flo

Monoclonal TPX2 Antibody (clone 18D5), Clone: 18D5

AMM01736G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human TPX2 (clone 18D5). The antibodies are raised in Mouse and are from clone 18D5. This antibody is applicable in WB and IHC-P

Monoclonal B3GAT1 Antibody (clone HCD57), Clone: HCD57

AMM01737G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human B3GAT1 (clone HCD57). The antibodies are raised in Mouse and are from clone HCD57. This antibody is applicable in IHC-P, Flo

Monoclonal CD74 Antibody (clone LN2), Clone: LN2

AMM01741G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human CD74 (clone LN2). The antibodies are raised in Mouse and are from clone LN2. This antibody is applicable in IHC-P, IP, IHC-Fr, Flo

Monoclonal CD9 Antibody (clone HI9a), Clone: HI9a

AMM01742G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human CD9 (clone HI9a). The antibodies are raised in Mouse and are from clone HI9a. This antibody is applicable in IHC-P, Flo

Monoclonal CD99 Antibody (clone HCD99), Clone: HCD99

AMM01743G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human CD99 (clone HCD99). The antibodies are raised in Mouse and are from clone HCD99. This antibody is applicable in IHC-P, Flo
This demonstrates that TMEJ can perform upstream of the Vacation junction resolvases to guard cells from lack of heterozygosity. Our work argues that Pol θ can thus compensate for the lack of the Holliday junction resolvases by utilizing homologous recombination intermediates, suppressing mitotic crossing over and preserving the genomic stability of cells.